DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox102F and sox2

DIOPT Version :9

Sequence 1:	NP_001014695.1	Gene:	Sox102F / 43844	FlyBaseID:	FBgn0039938	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_998283.1	Gene:	sox2 / 378723	ZFINID:	ZDB-GENE-030909-1	Length:	315	Species:	Danio rerio

Alignment Length:	205	Identity:	71/205 - (34%)
Similarity:	98/205 - (47%)	Gaps:	45/205 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   397 PSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARW 461
            |:.||...|.|:.:...:...:|...|||||||||||::.:|||:.:..|.||||.|||.|||.|
Zfish    12 PAPQPNTGGTGNTNSSGNNQKNSPDRIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEW 76

  Fly   462 KAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQL 526
            |.:|.::|:|:.:|..||..|||::||||:||||.|.              |.||:..:..:
Zfish    77 KLLSESEKRPFIDEAKRLRALHMKEHPDYKYRPRRKT--------------KTLMKKDKYTL--- 124

  Fly   527 WCRTGGVSGGSGSLCADACPKGSG-GSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCGHT---- 586
                      .|.|.|   |.|:| |:...|.....|.|....|        ::.|..|.|
Zfish   125 ----------PGGLLA---PGGNGMGAGVGVGAGLGAGVNQRMD--------SYAHMNGWTNGGY 168

  Fly   587 --PPQQFFYP 594
              ..:|..||
Zfish   169 GMMQEQLGYP 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	SOX-TCF_HMG-box	422..493	CDD:238684	40/70 (57%)
sox2	NP_998283.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..41		8/28 (29%)
		SOX-TCF_HMG-box	37..108	CDD:238684	40/70 (57%)
		SOXp	107..197	CDD:289133	25/110 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	235..263
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810