DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox102F and sox17

DIOPT Version :9

Sequence 1:	NP_001014695.1	Gene:	Sox102F / 43844	FlyBaseID:	FBgn0039938	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_571362.2	Gene:	sox17 / 30544	ZFINID:	ZDB-GENE-991213-1	Length:	413	Species:	Danio rerio

Alignment Length:	233	Identity:	74/233 - (31%)
Similarity:	106/233 - (45%)	Gaps:	65/233 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   381 DPESLNS---------GQ------LGPVPASPSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAF 430
            ||...:|         ||      |.|:..|.|........|.|.|      .|:|.|:||||||
Zfish    12 DPSQTSSCSSVMMPGMGQCPWVDPLSPLSDSKSKHEKCSAAGPGRG------KSEPRIRRPMNAF 70

  Fly   431 MVWAKDERRKILKACPDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPR 495
            ||||||||:::.:..||:||:.:||:||..|||:...||:|:.||..||...||:.||:|:||||
Zfish    71 MVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALPMVDKRPFVEEAERLRVKHMQDHPNYKYRPR 135

  Fly   496 PKRTCIVDGKKMRISEYKVLMRNRRAE----------MRQLWCRTGGVSGGSGS----LC----- 541
            .:               |.:.||:|.|          .:...|..|..:|.||:    .|
Zfish   136 RR---------------KQVKRNKRLEPSFPLPGMCDAKMTLCTEGMSAGYSGAGLPQYCENHTL 185

  Fly   542 --------ADACPKGSGGSN--SQVAVAAAAAVYHLQD 569
                    .|..|..:|.:.  :|:...:|.:.:|.|:
Zfish   186 FESYSLPTPDPSPMDAGTTEFFAQLQDQSAFSYHHQQE 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	SOX-TCF_HMG-box	422..493	CDD:238684	38/70 (54%)
sox17	NP_571362.2	SOX-TCF_HMG-box	62..133	CDD:238684	38/70 (54%)
sox17	NP_571362.2	Sox_C_TAD	186..411	CDD:288887	7/38 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910