Protein Alignment Sox102F and Sox5

DIOPT Version :9

• Sequence 1: NP_001014695.1
• Gene: Sox102F / 43844
• FlyBaseID: FBgn0039938
• Length: 618
• Species: Drosophila melanogaster
• Sequence 2: XP_006506994.1
• Gene: Sox5 / 20678
• MGIID: 98367
• Length: 792
• Species: Mus musculus
• Alignment Length: 687
• Identity: 211/687 - (30%)
• Similarity: 283/687 - (41%)
• Gaps: 231/687 - (33%)

  Fly    11 EKEHSDLGMIKQLQLIRNRILSQAHYD----SMTDIDASAQQ----QQQLQNVQRLQHESCLQEL 67
            |||...:|||.||..:|.::|: ||.:    :.:.|:...||    :||.:.:.| |.:..||:.
Mouse   225 EKERQLMGMINQLTSLREQLLA-AHDEQKKLAASQIEKQRQQMELAKQQQEQIAR-QQQQLLQQQ 287

  Fly    68 H--NHLSSQYGAVR------FTAANPQHQNQQAVSVSSGNLMPFLPAF-----LQPPMPNAQQLL 119
            |  |.|..|...|:      .....|..|...|.:...|.|:|  |.|     ...|.|     :
Mouse   288 HKINLLQQQIQQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLLP--PGFSYKAGCSDPYP-----V 345

  Fly   120 QLIPGHENAQSVPTHHHSHPQSEAFSTHKMALAPMWSTAAVAAAHIQ----AALAAAAVAAANNN 180
            ||||                     :|...|.|   :|..:....:|    |.|||..|:.
Mouse   346 QLIP---------------------TTMAAAAA---ATPGLGPLQLQQFYAAQLAAMQVSP---- 382

  Fly   181 KNSSHFSNNTNIVGLATRGNELLNTDSDPQMEIGETRRGGNGGSCRSRPESPTYENPPYEILSYS 245
                              |.:||..   ||         ||.|:..|
Mouse   383 ------------------GGKLLGL---PQ---------GNLGAAVS------------------ 399

  Fly   246 HNTPPESPHGRTADCSKNFSPSPTDNLSIASVSEAQDSEMDAPLNLS-KPKGSPSSSPNSSSQRD 309
                |.|.|   .|.|.| ||.|          :::| |:..||||| |||.|...|| :|....
Mouse   400 ----PTSIH---TDKSTN-SPPP----------KSKD-EVAQPLNLSAKPKTSDGKSP-ASPTSP 444

  Fly   310 HCENLT------PVVSSPPLSWHQGQPHYAEIELPLLKSHGRVWNSAV---------------AC 353
            |...|.      |:.:|.|.:  ...|......:..|..|..| ..|:               |.
Mouse   445 HMPALRINSGAGPLKASVPAA--LASPSARVSTIGYLNDHDAV-TKAIQEARQMKEQLRREQQAL 506

  Fly   354 SGGSRATRVSRDSVNSCGTNSERSAALDPESLN----------------------SGQLGPVPAS 396
            .|  :...|:...:::|.|..|::..   |||.                      ||........
Mouse   507 DG--KVAVVNSIGLSNCRTEKEKTTL---ESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGV 566

  Fly   397 PSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACPDMHNSNISKILGARW 461
            ..|:..|:..|.|        .::||||||||||||||||||||||:|.|||||||||||||:||
Mouse   567 SESRIYRESRGRG--------SNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRW 623

  Fly   462 KAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISEYKVLMRNRRAEMRQL 526
            |||:|.:||||||||:||||.|:|::|||:|:|||||||:|||||:||.|||.:|||||.||||.
Mouse   624 KAMTNLEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQY 688

  Fly   527 WCRTGGVSGGSGSLCADACPKGSGGSNSQVAVAAAAAVYHLQDMASSAASTAHGHDCGHTPPQQF 591
            :                     :.|..:|:.:|.|..||      .||.:.| |....|.|.:
Mouse   689 F---------------------NVGQQAQIPIATAGVVY------PSAIAMA-GMPSPHLPSE-- 723

  Fly   592 FYPPESLSPS----------GFSSDEVELASQRELDD 618
             :...|.||.          |...:|..:..:.:.:|
Mouse   724 -HSSVSSSPEPGMPVIQSTYGAKGEEPHIKEEIQAED 759

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	SOX-TCF_HMG-box	422..493	CDD:238684	58/70 (83%)
Sox5	XP_006506994.1	SOX-TCF_HMG-box	584..655	CDD:238684	58/70 (83%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838578
Domainoid	1	1.000	128	1.000	Domainoid score	I5294
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3733
Isobase	1	0.950	-	0	Normalized mean entropy	S3575
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003460
OrthoInspector	1	1.000	-	-		otm42560
orthoMCL	1	0.900	-	-		OOG6_106215
Panther	1	1.100	-	-	O	PTHR45789
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4059
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.820