DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sox102F and Sox17

DIOPT Version :9

Sequence 1:	NP_001014695.1	Gene:	Sox102F / 43844	FlyBaseID:	FBgn0039938	Length:	618	Species:	Drosophila melanogaster
Sequence 2:	NP_001276393.1	Gene:	Sox17 / 20671	MGIID:	107543	Length:	419	Species:	Mus musculus

Alignment Length:	240	Identity:	76/240 - (31%)
Similarity:	108/240 - (45%)	Gaps:	44/240 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 LGPVPASPSSQPLRQGNGHGH--------GGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKACP 446
            |||.|.:.|..||......|.        .|..|...::..|:||||||||||||||:::.:..|
Mouse    27 LGPCPWAESLSPLGDVKVKGEVVASSGAPAGTSGRAKAESRIRRPMNAFMVWAKDERKRLAQQNP 91

  Fly   447 DMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRISE 511
            |:||:.:||:||..|||::.|:|:|:.||..||...||:.||:|:||||.:
Mouse    92 DLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRR-------------- 142

  Fly   512 YKVLMRNRRAEMRQLWCRTGG-----VSGGSGSLCADACPKGSGGSNSQVAVAAAAAVYHLQDMA 571
             |.:.|.:|.|        ||     |...:|:|    .|:|...:...:.:......|......
Mouse   143 -KQVKRMKRVE--------GGFLHALVEPQAGAL----GPEGGRVAMDGLGLPFPEPGYPAGPPL 194

  Fly   572 SSAASTAHGHDC-GHTPPQQFFYP---PESLSPSGFSSDEVELAS 612
            .|.....|..|| |...|....||   |::....|...|....|:
Mouse   195 MSPHMGPHYRDCQGLGAPALDGYPLPTPDTSPLDGVEQDPAFFAA 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sox102F	NP_001014695.1	SOX-TCF_HMG-box	422..493	CDD:238684	38/70 (54%)
Sox17	NP_001276393.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..27		76/240 (32%)
		SOX-TCF_HMG-box	67..138	CDD:238684	38/70 (54%)
		Sox17_18_mid	203..253	CDD:403331	10/37 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..356
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0527
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810