DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sox102F and Sox9

DIOPT Version :9

Sequence 1:NP_001014695.1 Gene:Sox102F / 43844 FlyBaseID:FBgn0039938 Length:618 Species:Drosophila melanogaster
Sequence 2:NP_536328.1 Gene:Sox9 / 140586 RGDID:620474 Length:507 Species:Rattus norvegicus


Alignment Length:348 Identity:79/348 - (22%)
Similarity:120/348 - (34%) Gaps:136/348 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   257 TADCSKNFSPSPTDNLSIASV------SEAQDSEMDAPLNLSKPKGSPSSSPNSSSQRDHCENLT 315
            |.:..|..|.:|:..:|..|.      ....|:|...|...:.|||.|.....|.      |:..
  Rat    11 TDEQEKGLSGAPSPTMSEDSAGSPCPSGSGSDTENTRPQENTFPKGEPDLKKESE------EDKF 69

  Fly   316 PVVSSPPLSWHQGQPHYAEIELPLLKSHGRVWNSAVACSGGSRATRVSRDSVNSCGTNSERSAAL 380
            ||.....:|             .:||  |..|.                                
  Rat    70 PVCIREAVS-------------QVLK--GYDWT-------------------------------- 87

  Fly   381 DPESLNSGQLGPVPASPSSQPLRQGNGHGHGGNHGHVHSKPHIKRPMNAFMVWAKDERRKILKAC 445
                     |.|:|...                :|...:|||:|||||||||||:..|||:....
  Rat    88 ---------LVPMPVRV----------------NGSSKNKPHVKRPMNAFMVWAQAARRKLADQY 127

  Fly   446 PDMHNSNISKILGARWKAMSNADKQPYYEEQSRLSKLHMEQHPDYRYRPRPKRTCIVDGKKMRIS 510
            |.:||:.:||.||..|:.::.::|:|:.||..||...|.:.||||:|:||.:::           
  Rat   128 PHLHNAELSKTLGKLWRLLNESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKS----------- 181

  Fly   511 EYKVLMRNRRAEMRQLWCRTGGVSGGSGSLCADACPKGSGGSNSQVAVAAAAAVYHLQ-DMASSA 574
                 ::|.:||..:                          :..|..::..|....|| |...|:
  Rat   182 -----VKNGQAEAEE--------------------------ATEQTHISPNAIFKALQADSPHSS 215

  Fly   575 ASTAHGHDCGH---------TPP 588
            :..:..|..|.         |||
  Rat   216 SGMSEVHSPGEHSGQSQGPPTPP 238

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sox102FNP_001014695.1 SOX-TCF_HMG-box 422..493 CDD:238684 34/70 (49%)
Sox9NP_536328.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..67 14/61 (23%)
Sox_N 22..94 CDD:403592 22/133 (17%)
Dimerization (DIM). /evidence=ECO:0000250|UniProtKB:P48436 63..103 13/117 (11%)
PQA. /evidence=ECO:0000250|UniProtKB:P48436 63..103 13/117 (11%)
SOX-TCF_HMG-box 104..174 CDD:238684 34/69 (49%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 160..271 24/121 (20%)
Transactivation domain (TAM). /evidence=ECO:0000250|UniProtKB:P48436 224..307 4/15 (27%)
9aaTAD 1. /evidence=ECO:0000250|UniProtKB:P48436 275..284
9aaTAD 2. /evidence=ECO:0000250|UniProtKB:P48436 290..298
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 335..429
Transactivation domain (TAC). /evidence=ECO:0000250|UniProtKB:P48436 392..507
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 477..507
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166342354
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.830

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