DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and foxc1b

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_571804.1	Gene:	foxc1b / 79375	ZFINID:	ZDB-GENE-010302-2	Length:	433	Species:	Danio rerio

Alignment Length:	366	Identity:	100/366 - (27%)
Similarity:	150/366 - (40%)	Gaps:	121/366 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 GTGGSGASAPWLHLSPYGHHGSGSLPSVNRMAALSTISLFP-QTQRIFQPEEP--------KPQH 132
            |.|.:|..||   :|.|.|               :|...:| ...|.:.|..|        ||.:
Zfish    31 GGGYTGMPAP---MSMYSH---------------ATHEQYPGGMARAYGPYAPAQQPKDMVKPPY 77

  Fly   133 SYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSAN-- 195
            |||.||.|||.:|:|.|:.|:.|||:|::.:|::|....||:||||||||||:||:|..|...
Zfish    78 SYIALITMAIQNSSDKKITLNGIYQFIMERFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDKKP 142

  Fly   196 GKGHYWAIHPANMEDFRKGDFRRRK---------AQRKVRKHMG---------------LSVDDA 236
            |||.||.:.|.:...|..|.|.||:         .:::.|...|               :.:.|.
Zfish   143 GKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDVLREKEDRDRQGKDNPGQACEQDAQQPVKLRDI 207

  Fly   237 STDSPS-PPPLDLTTPP--------------------PPSSQSALQLSAL--------GYPYHQH 272
            .|::.: .||.| :|||                    .|.||:..|..::        |.|.|..
Zfish   208 KTENGACTPPHD-STPPLSTVPKTESPDRSGGSACSGSPQSQTPQQAFSMDTIMTGLRGSPQHAA 271

  Fly   273 YIGQFFNRSSAPGM-----------THYSPP--DPALLMQRQEANNL--------DQTIQPTQLQ 316
            .:..  :|::.||.           .|||||  .||......:|.:|        |.|:.
Zfish   272 ELPA--SRAALPGSVSLTYSPTPQPAHYSPPCGQPATYHCNMQATSLYTGDRGHGDDTLP----- 329

  Fly   317 QPHSHHQHFAYINSTTTTTIANMF-SQTRKRQFDVASLLAP 356
                     .|.|:|..::|::.. |.:::.|....:.|||
Zfish   330 ---------EYTNTTNASSISHPHQSSSQESQHLQQNRLAP 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	43/85 (51%)
foxc1b	NP_571804.1	Forkhead	74..160	CDD:278670	43/85 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..250		13/76 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	318..355		8/50 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820