DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and FOXD4L6

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001078945.1	Gene:	FOXD4L6 / 653404	HGNCID:	31986	Length:	417	Species:	Homo sapiens

Alignment Length:	248	Identity:	82/248 - (33%)
Similarity:	112/248 - (45%)	Gaps:	62/248 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 LRCPQYGGT--------GGSGASAPWLHLSPYGHHGSGSLPSVNRMAALSTISLFPQTQRIFQPE 126
            |:..::||.        ||.|.|.|    |.:|    ....:..|.||.|..:..|
Human    59 LQVARWGGVALPREHIEGGGGPSDP----SEFG----TKFRAPPRSAAASEDARQP--------- 106

  Fly   127 EPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSG 191
             .||.:|||.||.||||.:...:|.||.|..:|...:||:|.:.|.|:|||||||||||||:|..
Human   107 -AKPPYSYIALITMAILQNPHKRLTLSGICAFISGRFPYYRRKFPAWQNSIRHNLSLNDCFVKIP 170

  Fly   192 RSAN--GKGHYWAIHPANMEDFRKGDFRRRKAQRKVRKH-----------MGLSVDDASTDSPSP 243
            |...  |||:||::.||:.:.|..|.|.||:  ::.::|           ..|....|:..:|.|
Human   171 REPGHPGKGNYWSLDPASQDMFDNGSFLRRR--KRFKRHQLTPGAHLPHPFPLPAAHAALHNPHP 233

  Fly   244 PPLDLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYS--PPDP 294
            .|| |..|.||.....      .||            ::|||...|:  .|.|
Human   234 GPL-LGAPAPPQPVPG------AYP------------NTAPGRRPYALLHPHP 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/85 (52%)
FOXD4L6	NP_001078945.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	70..105		11/42 (26%)
		Forkhead	108..194	CDD:278670	44/85 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820