DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and Foxb1

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_071773.2	Gene:	Foxb1 / 64290	MGIID:	1927549	Length:	325	Species:	Mus musculus

Alignment Length:	194	Identity:	74/194 - (38%)
Similarity:	99/194 - (51%)	Gaps:	37/194 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 EPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSG 191
            :.||.:|||.|.||||.||.:..|.||:||::|:|.:||:|.....|:||:|||||.||||||..
Mouse    11 DQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIP 75

  Fly   192 RSAN--GKGHYWAIHPANMEDFRKGDFRRRKAQRKVRKHMGLSVDDASTDSPSPPPLDLTTPPPP 254
            |..:  |||.:||:||:..:.|..|.|.||:.:.||     |..|..:...|:.....|
Mouse    76 RRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKV-----LKSDHLAPSKPADAAQYL------ 129

  Fly   255 SSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYSPPDPALLMQRQEANNLDQTIQPTQLQQP 318
            ..|:.|:||||                :|.| ||. |..||      .|.||....||:..:.|
Mouse   130 QQQAKLRLSAL----------------AASG-THL-PQMPA------AAYNLGGVAQPSGFKHP 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	45/85 (53%)
Foxb1	NP_071773.2	FH	13..101	CDD:214627	45/87 (52%)
Foxb1	NP_071773.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	284..325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11829
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040