DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and Foxj2

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_068699.1	Gene:	Foxj2 / 60611	MGIID:	1926805	Length:	565	Species:	Mus musculus

Alignment Length:	397	Identity:	99/397 - (24%)
Similarity:	137/397 - (34%)	Gaps:	155/397 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 IERL-RCPQYGGTGGSGASAPWLHLSPYGHHGSGSLPSVNRMAALSTISLFPQTQRIFQPEEPKP 130
            ||:| ...|.|..||:...:|          ||.:.|:       :|:|    .......::.||
Mouse    24 IEKLGSASQAGPPGGARKCSP----------GSPTDPN-------ATLS----KDEAAVHQDGKP 67

  Fly   131 QHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSAN 195
            ::||..||..||.||...|:.||:||::|.||:||:::.|.||:||||||||||.||.|..|..:
Mouse    68 RYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRD 132

  Fly   196 --GKGHYWAI-----------HPANMEDFRKGDFRRRKAQRKVR-----------KHMGL----- 231
              |||.||.|           ||.  :|....|...::|.:..|           .|.|.
Mouse   133 DPGKGSYWTIDTCPDISRKRRHPP--DDDLSQDSPEQEASKSPRGGVPGSGEASLSHEGTPQMSL 195

  Fly   232 --------------SVDDASTDSPSP--------PPLDLTTPPPPSSQSALQLSALGYPYHQHYI 274
                          |||..:..:.:|        |||..|......|.|.:....|.:.:...|.
Mouse   196 QSPSSVANYSQGPGSVDGGAVAAGAPGQESTEGAPPLYNTNHDFKFSYSEINFQDLSWSFRNLYK 260

  Fly   275 GQFFNRSSA------------PGMTHY--------------SPPDPALLMQRQEA-----NNL-- 306
            ......||:            |...:|              .||......|:|:|     :|:
Mouse   261 SMLERSSSSQHGFSSLLGDMPPSNNYYVYQQQQQQQPPPQPQPPPQQPQPQQQQAPTQGPSNVGG 325

  Fly   307 -----------------------------DQTIQPTQLQ----QPHSHHQHF------------- 325
                                         ...:.|..||    .||.||.|.
Mouse   326 APPLHTPSPDGCTTPGGKQAGAEGYGPPTGMAMHPPPLQHGGYHPHQHHPHSHPAQQPPQPQAQS 390

  Fly   326 -AYINST 331
             |.||||
Mouse   391 QASINST 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	46/96 (48%)
Foxj2	NP_068699.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..61		10/52 (19%)
		Forkhead	66..143	CDD:278670	42/76 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	125..233		22/109 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..399		19/108 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..565
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820