Protein Alignment fd102C and foxo4

DIOPT Version :10

• Sequence 1: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_009289443.1
• Gene: foxo4 / 563719
• ZFINID: ZDB-GENE-150311-1
• Length: 626
• Species: Danio rerio
• Alignment Length: 643
• Identity: 121/643 - (18%)
• Similarity: 199/643 - (30%)
• Gaps: 262/643 - (40%)

  Fly    27 VPKPSLPNIYPLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTGGSGASAPWLHLS 91
            :|:|.:..: ..|.|..|::.:.|...|:.:........:.|::...:.|...|.|.:.|
Zfish    26 LPRPDISAV-KAGGTDGSESAAGTPPAEEDKHDPQPIICDPEKIAVSEGGLVAGVGGATP----- 84

  Fly    92 PYGHHGSGSLPSVNRMAALSTISLFPQTQRIFQPEEPKPQHSYIGLIAMAILSSTDMKLVLSDIY 156
               ..||      :|..|..                   ..||..||:.||.:|.:.:|.|:.||
Zfish    85 ---RKGS------SRRNAWG-------------------NQSYADLISQAIENSPEKRLTLAQIY 121

  Fly   157 QYILDNYPYFRSRG-----PGWRNSIRHNLSLNDCFIKSGRSANGKGHYWAIHPANMEDFRKGDF 216
            .:::...|||:.:|     .||:|||||||||::.|::....:.||..:|.::|   |..:.|..
Zfish   122 DWMVKTVPYFKDKGDSNSSAGWKNSIRHNLSLHNKFLRVHNESTGKSSWWMLNP---EGGKTGKA 183

  Fly   217 RRRKA---------------QRKVRKHMGL--------------SVDDASTDSPSPP-------- 244
            .||:|               .::.:|..|.              :....:.|||.||
Zfish   184 HRRRATSMDNSGKLLKSRIRAKQTKKQAGAAGIGGTGGGLQGEGTSGTGNADSPGPPGQFGKWGV 248

  Fly   245 -------------PLDLTTPPPPSSQSALQLSALGYPY-----------HQHYIGQFFNRS---- 281
                         |...|:..|.:|.:|..||....|.           ....:|.:.:.:
Zfish   249 NSSSPSSRGSLDDPDIWTSIRPRTSSNASTLSGRLSPIATGQEDEDDLPEDGLLGGYSSGNLPST 313

  Fly   282 ------------------------SAPGMTHYSPPDP----ALLMQRQEANNLDQTIQPTQLQQ- 317
                                    ::|.|...:||.|    :.|:.|..:....:.:|||:..|
Zfish   314 LPETLMEELDLIDGLTLMTAPQGGASPSMAPPAPPQPLPSASTLLPRGSSFPSFRQLQPTKASQG 378

  Fly   318 -----PHSHHQHFAYINSTTTTTIANMF-------------------------------SQTRKR 346
                 |.|..|..|..::::.:...|..                               |.....
Zfish   379 STPPGPQSSVQPNAGSSTSSPSNFGNSLFSPLPGPGHSGFSTHVPSSLEALLTSDSPPPSDVMMT 443

  Fly   347 QFDV--------------ASLLAPDVQI--------VDIVSEDQESSVTPTTSAR---------- 379
            |.|.              .|:.:..|:.        :|..:..|.|...|.....
Zfish   444 QMDPLMPSQGGGGLLGLGGSMSSSQVKAGQMMLSKGIDTSTVGQMSLQRPPQLQHSQMGFGMMHM 508

  Fly   380 ---------TTTQTHHTVITKQTIHREVV---------LGLEK--------PVQD---ADIDADI 415
                     :|.:|.|.|.....:|..|:         .||.:        |.||   .|:|.|:
Zfish   509 AMSQEPPQLSTVKTQHQVPGSGLLHHGVIPSPAGNGGLQGLGQFSTMPCFIPSQDRLPTDLDIDM 573

  Fly   416 DVEVNVDVVDDSIIPDTDSYTDGEDRKKTRGTLKQIFSIEDNNSYLIDGRLSSFDADP 473
            ..| |:|...:.||                            ||.|:||.|..|:.||
Zfish   574 FTE-NLDCDVEYII----------------------------NSDLMDGDLVDFNFDP 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	FH_FOXQ2-like	129..223	CDD:410809	36/113 (32%)
foxo4	XP_009289443.1	FH_FOXO4	91..176	CDD:410836	32/106 (30%)
		FOXO_KIX_bdg	375..>450	CDD:465228	9/74 (12%)
		FOXO-TAD	564..603	CDD:435506	17/68 (25%)