Protein Alignment fd102C and FOXB2

DIOPT Version :10

• Sequence 1: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001013757.1
• Gene: FOXB2 / 442425
• HGNCID: 23315
• Length: 432
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 86/312 - (27%)
• Similarity: 117/312 - (37%)
• Gaps: 84/312 - (26%)

  Fly   127 EPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSG 191
            :.||.:|||.|.||||..|.:..|.|||||::|::.:||:|.....|:||:|||||.||||||..
Human    11 DQKPPYSYISLTAMAIQHSAEKMLPLSDIYKFIMERFPYYREHTQRWQNSLRHNLSFNDCFIKIP 75

  Fly   192 RSAN--GKGHYWAIHPANMEDFRKGDFRRRKAQRKVRKHMGLSVDDASTDS-------------- 240
            |..:  |||.:||:||...:.|..|.|.||:.:.||.:.....:...||.|
Human    76 RRPDQPGKGSFWALHPDCGDMFENGSFLRRRKRFKVLRADHTHLHAGSTKSAPGAGPGGHLHPHH 140

  Fly   241 ----------------------PSPPPLDLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSA 283
                                  |.|||     ||||..           |:..||.
Human   141 HHHPHHHHHHHAAAHHHHHHHPPQPPP-----PPPPPP-----------PHMVHYF--------- 180

  Fly   284 PGMTHYSP---PDPALLMQRQEANNLDQTIQPTQLQQPHSHHQHFAYINSTTTTTIANMFSQTRK 345
                |..|   |.|...:..|......|..||.|...|....:..|...:......|.:.|..|.
Human   181 ----HQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPGKMQEAAAVAAAAAAAAAAAVGSVGRL 241

  Fly   346 RQFDVASLLAPDVQIVDIVSEDQESSVTPTTSARTTTQTHHTVITKQTIHRE 397
            .||....|              ..::.....:|.:|:...|....:..|.|:
Human   242 SQFPPYGL--------------GSAAAAAAAAAASTSGFKHPFAIENIIGRD 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	FH_FOXQ2-like	129..223	CDD:410809	48/95 (51%)
FOXB2	NP_001013757.1	FH_FOXB2	1..110	CDD:410817	48/98 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..220		24/130 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	413..432