Protein Alignment fd102C and FOXA1

DIOPT Version :9

• Sequence 1: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_004487.2
• Gene: FOXA1 / 3169
• HGNCID: 5021
• Length: 472
• Species: Homo sapiens
• Alignment Length: 397
• Identity: 103/397 - (25%)
• Similarity: 149/397 - (37%)
• Gaps: 103/397 - (25%)

  Fly    14 ADQDQGTSSRDSNVPKPSLPNIYPLGTTRTSQAQSTT--MTLEQYRLQLYNYALNIERLRCPQYG 76
            ||..:..||...:.....|.::..:.|..|....:|:  ||...:.:...|..|..........|
Human    20 ADTQEAYSSVPVSNMNSGLGSMNSMNTYMTMNTMTTSGNMTPASFNMSYANPGLGAGLSPGAVAG 84

  Fly    77 GTGGS----------GASAPWLHLSP--YGHHGSGSLPSVNRMA--------ALSTISLFPQT-- 119
            ..|||          |.:|....|||  .|..|:....|:|.:.        .:|.::..|..
Human    85 MPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLG 149

  Fly   120 ---------QRIFQPEEP--KPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGW 173
                     .:.|:...|  ||.:|||.||.|||..:....|.||:|||:|:|.:||:|.....|
Human   150 RSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRW 214

  Fly   174 RNSIRHNLSLNDCFIKSGRSAN--GKGHYWAIHPANMEDFRKGDFRRRKAQRKVRKHMGL----- 231
            :|||||:||.||||:|..||.:  |||.||.:||.:...|..|.:.||:.:.|..|..|.
Human   215 QNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHPDSGNMFENGCYLRRQKRFKCEKQPGAGGGGG 279

  Fly   232 -------------------SVDDASTDSP----------------------SPPPLD-------- 247
                               ...:.|.|||                      ||..||
Human   280 SGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLDHSGATATG 344

  Fly   248 ----LTTP----PPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYSPPDP----ALLMQR 300
                |.||    .||.|.....|:::...:..|.:....::....|..|||...|    .|:...
Human   345 GASELKTPASSTAPPISSGPGALASVPASHPAHGLAPHESQLHLKGDPHYSFNHPFSINNLMSSS 409

  Fly   301 QEANNLD 307
            ::.:.||
Human   410 EQQHKLD 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/85 (52%)
FOXA1	NP_004487.2	Forkhead_N	17..169	CDD:369872	29/148 (20%)
		FH_FOXA1	157..268	CDD:410812	49/110 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	269..392		19/122 (16%)
		HNF_C	398..461	CDD:401339	4/19 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910