DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and Foxk1

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001032296.2	Gene:	Foxk1 / 304298	RGDID:	1309643	Length:	719	Species:	Rattus norvegicus

Alignment Length:	475	Identity:	127/475 - (26%)
Similarity:	190/475 - (40%)	Gaps:	111/475 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 EEPKPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKS 190
            :|.||.:||..||..||.|:.|.:|.||.||.:|..:|||:|:...||:||||||||||..|||.
  Rat   288 DESKPPYSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRYFIKV 352

  Fly   191 GRSAN--GKGHYWAIHPANMEDFRKGDFRRRKAQRKV---RKHMGLSVDDASTDSPSPPPLDLTT 250
            .||..  |||.:|.|.||:.....:..||:|: ||.|   |...|.....::..||:.|  .|.:
  Rat   353 PRSQEEPGKGSFWRIDPASEAKLVEQAFRKRR-QRGVSCFRTPFGPLSSRSAPASPTHP--GLMS 414

  Fly   251 PPPPSSQSALQLSALGYPY-HQHYIG-------QFFNRSSAPG-------MTHYSPPDPALLMQR 300
            |.....|:...||..|.|. |...:|       ::....||||       :....||.|:.|:.:
  Rat   415 PRSSGLQTPECLSREGSPIPHDPDLGSKLASVPEYRYSQSAPGSPVSAQPVIMAVPPRPSNLVAK 479

  Fly   301 QEANNLDQTIQPTQL---QQPHSHHQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDVQIVD 362
            ..|      ..|..:   |||..|..|...                          .||.|.:|.
  Rat   480 PVA------YMPASIVTSQQPSGHAIHVVQ--------------------------QAPTVTMVR 512

  Fly   363 IVSEDQESSVTPTTSARTTTQTHHTVITKQTIHREVVLGL--------EKP-VQDADIDADIDVE 418
            :|:....|:.....:::.:|.|.|.  |..|    .||.|        ||| :..|.|.|...|
  Rat   513 VVTTSANSANGYILASQGSTATSHD--TAGT----AVLDLGNEARGLEEKPTIAFATIPAASRV- 570

  Fly   419 VNVDVVDDSIIPDTDSYTDGEDRKKTRGTLKQ----IFSIEDNNSYLIDGRLSSFDADPDHDPDH 479
              :..|...:.|....:|....:..|..|:.|    :.::..|..:.:
  Rat   571 --IQTVASQMAPGVPGHTVTILQPATPVTIGQHHLPVRAVTQNGKHAV----------------- 616

  Fly   480 DPEDLEQHNFSIASSAARSLGSSSSQHEESSSLEECPIQECIVAPQ--TALISSMATA------K 536
             |.:....|....:|..:.|.:     :.|||......:.|.|.|:  ||.:|..|:|      .
  Rat   617 -PTNNLTGNAYALTSPLQLLAA-----QASSSTPVVITRVCEVGPEEPTAAVSVAASAAPTPAIS 675

  Fly   537 TSTLSVPISDAYLELNQVDQ 556
            |:|.:....:..|:.::|::
  Rat   676 TTTSASSSGEPELKRSRVEE 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/85 (52%)
Foxk1	NP_001032296.2	FHA	<88..190	CDD:224630
		FHA	96..189	CDD:238017
		Forkhead	291..377	CDD:278670	44/85 (52%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820