DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and Foxk2

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_006247952.1	Gene:	Foxk2 / 303753	RGDID:	1305408	Length:	650	Species:	Rattus norvegicus

Alignment Length:	439	Identity:	126/439 - (28%)
Similarity:	166/439 - (37%)	Gaps:	142/439 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 KPSLPNIYPLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTGGSGASAPWLHLSPY 93
            ||..|:|.||           |:.:......|      |..|..|.  ||..:..|.|   .||.
  Rat   164 KPVQPHISPL-----------TINIPDTMAHL------ISPLPSPT--GTISAANSCP---SSPR 206

  Fly    94 GHHGSG-----SLPS-VNRMAALSTISLFPQTQRIFQPE-------------EPKPQHSYIGLIA 139
            |...||     .:|| :|.||..|            |||             :.||.:||..||.
  Rat   207 GAGSSGYKMGRVIPSDLNLMADNS------------QPENEKEASGGDSPKDDSKPPYSYAQLIV 259

  Fly   140 MAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSAN--GKGHYWA 202
            .||..:.|.:|.|:.||.:|..||||:|:...||:||||||||||..|||..||..  |||.:|.
  Rat   260 QAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWR 324

  Fly   203 IHPANMEDFRKGDFRRRK--------------AQRKV---RKHMG-LSVDDASTDSP-------S 242
            |.||:.....:..||:|:              :.|..   ..|.| ||...:...:|       |
  Rat   325 IDPASESKLVEQAFRKRRPRGVPCFRTPLGPLSSRSAPASPNHAGVLSAHSSGAQTPESLSREGS 389

  Fly   243 PPPLDLTTPPPPSSQSALQLSALGYPYHQHYIGQFFNRSSAPGMTHYSPPDPALLMQRQEANNLD 307
            |.||:   |.|.:||..|.:           |.:.....||||....|.| ..:.:|||    |.
  Rat   390 PAPLE---PEPGASQPKLAV-----------IQEARFAQSAPGSPLSSQP-VLITVQRQ----LP 435

  Fly   308 QTIQPTQLQQPHSHHQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDVQIVDIVSEDQESSV 372
            ..|:|               :..|..|.:....||            .|.||.|.:|.:....:|
  Rat   436 PAIKP---------------VTYTVATPVTTPTSQ------------PPVVQTVHVVHQIPAVAV 473

  Fly   373 TPTTS---ARTTTQTHHTVITKQTI------------HREVVLGLEKPV 406
            |....   |.|.|.....|:|:..:            ||||.:.:| ||
  Rat   474 TSVAGLAPANTYTVAGQAVVTQAAVLAPKTEPQENGDHREVRVKVE-PV 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	43/85 (51%)
Foxk2	XP_006247952.1	FHA	41..145	CDD:238017
Foxk2	XP_006247952.1	Forkhead	249..335	CDD:278670	43/85 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820