Protein Alignment fd102C and Foxo3

DIOPT Version :10

• Sequence 1: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001099865.1
• Gene: Foxo3 / 294515
• RGDID: 1309196
• Length: 672
• Species: Rattus norvegicus
• Alignment Length: 581
• Identity: 124/581 - (21%)
• Similarity: 210/581 - (36%)
• Gaps: 153/581 - (26%)

  Fly    78 TGGSGASAPWLH-------------------LSPYGHH-GSGSLPSVNRMAALSTISLFPQTQRI 122
            :||.|:||..:.                   |||.|.. |:|...|...::.        .||..
  Rat    69 SGGRGSSAMVIGGGVSSALGSGLLLEDSARLLSPGGQDLGTGPASSAGALSG--------GTQTQ 125

  Fly   123 FQPEEPKP------------------------QHSYIGLIAMAILSSTDMKLVLSDIYQYILDNY 163
            .||::|.|                        ..||..||..||.||.|.:|.||.||::::...
  Rat   126 LQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCV 190

  Fly   164 PYFRSRG-----PGWRNSIRHNLSLNDCFIKSGRSANGKGHYWAIHPANMEDFRKGDFRRRKA-- 221
            |||:.:|     .||:|||||||||:..|::......||..:|.|:|   :..:.|...||:|
  Rat   191 PYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINP---DGGKSGKAPRRRAVS 252

  Fly   222 ---QRKVRKHMGLSVD-----DASTDSPSPPPLDLTT-PPPPSSQSALQLSALGYPYHQHYIGQF 277
               ..|..|..|.:..     .|:.:|....|..|:. |..|:|:|:.:|.|.         ..|
  Rat   253 MDNSNKYTKSRGRAAKKKAALQAAPESADDSPSQLSKWPGSPTSRSSDELDAW---------TDF 308

  Fly   278 FNRSSAPGMTHYSPPDPALL-MQRQEANNLDQTIQPTQLQQPHSHHQHFAYINSTT-TTTIANMF 340
            .:|:::...|......|.|. .:..:..:.|..:.|            ..|.:|.: :.:::...
  Rat   309 RSRTNSNASTVSGRLSPILASTELDDVQDDDGPLSP------------MLYSSSASLSPSVSKPC 361

  Fly   341 SQTRKRQFDVASLLAPDVQIVDIVSED-------------------QESSVTPTTSART-----T 381
            :....|..|:|..:..:..:.:.:.:|                   |.||..|.|:..:     |
  Rat   362 TVELPRLTDMAGTMNLNDGLAENLMDDLLDNIALPPSQASPPGGLMQRSSSFPYTAKSSGLGSPT 426

  Fly   382 TQTHHTVI-----------TKQTIHREVVLGLEKPVQDADIDADIDVEVNVDVVDDSIIPDTDSY 435
            :..:.||.           ..|||..      .:|...:.:.     ......:.|.:..|:.|:
  Rat   427 SSFNSTVFGPASLNSLRQSPMQTIQE------NRPATFSSVS-----HYGNQTLQDLLTSDSLSH 480

  Fly   436 TD----GEDRKKTRGTLKQIFSIEDNNSYLIDGRLSSFDADPDHDPDHDPEDL-EQHNFSIASSA 495
            :|    ..|...::.:..........|..|.:..:.||.|.|......:...| .||....|...
  Rat   481 SDVMMTQSDPLMSQASTAVSAQNARRNVMLRNDPMMSFAAQPTQGSLVNQNLLHHQHQTQGALGG 545

  Fly   496 ARSLGSSSSQH--EESSSL------EECPIQECIVAPQTALISSMATAKTSTLSVPISDAY 548
            :|:|.:|.|..  .:||||      ::.|:.:.:.....:|..|...:.::.|.|...|.:
  Rat   546 SRALSNSVSNMGLSDSSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSASANLPVMGHDKF 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	FH_FOXQ2-like	129..223	CDD:410809	40/127 (31%)
Foxo3	NP_001099865.1	FH_FOXO3	156..238	CDD:410835	35/84 (42%)
		FOXO_KIX_bdg	431..510	CDD:465228	12/89 (13%)
		FOXO-TAD	605..643	CDD:435506	0/2 (0%)