DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and Foxj3

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001344106.1	Gene:	Foxj3 / 230700	MGIID:	2443432	Length:	623	Species:	Mus musculus

Alignment Length:	337	Identity:	97/337 - (28%)
Similarity:	144/337 - (42%)	Gaps:	89/337 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 HGSGSLPSVNRMAALSTISLFPQT----QRIFQPEEPKPQHSYIGLIAMAILSSTDMKLVLSDIY 156
            ||:|    :::..||    |.|.|    :.:.|.::.||.:||..||..||.||...|:.||:||
Mouse    49 HGTG----ISKKNAL----LDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIY 105

  Fly   157 QYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSAN--GKGHYWAIHPANMEDFRKGDFRRR 219
            |:|.||:||:|..|.||:||||||||||.||:|..||.:  |||.||||.....||..  ..|.:
Mouse   106 QWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTL--PTRPK 168

  Fly   220 KAQRKV-RKHMGLSVDDAS------TDSPSPPPLDLTT----------------PPPPSSQSALQ 261
            |..|.| |.....|:|..|      ....:.|.|.:.|                .|..|..::|.
Mouse   169 KRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNADQDGSDSPRSSLNNSLS 233

  Fly   262 LSALGYPYHQHYIGQFFNRSSAPGMTHYSP----PDPALLMQRQEANNLDQTIQPTQLQQPHSH- 321
            ..:|.          ..|.:|...:..|:|    |:|           :.|.:.|.|.|||..:
Mouse   234 DQSLA----------SVNLNSVGSVHSYTPVTNHPEP-----------VSQPLTPQQQQQPQYNL 277

  Fly   322 ----------HQHFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDVQIVDIVSEDQESSVTPTT 376
                      ..:|..::::..:...::|.|:..:|           .::.|.||..:.|.|..:
Mouse   278 PEREKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQ-----------GLMSIPSESSQQSHTSCS 331

  Fly   377 ---SARTTTQTH 385
               |..:|..:|
Mouse   332 YQHSPSSTVTSH 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	49/85 (58%)
Foxj3	NP_001344106.1	COG5025	<54..347	CDD:227358	94/328 (29%)
		Forkhead	78..155	CDD:365978	46/76 (61%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	143..178		14/36 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..275		10/37 (27%)
		PAT1	<311..>434	CDD:370676	9/44 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	316..451		8/28 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820