DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and FOXE1

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_004464.2	Gene:	FOXE1 / 2304	HGNCID:	3806	Length:	373	Species:	Homo sapiens

Alignment Length:	162	Identity:	63/162 - (38%)
Similarity:	82/162 - (50%)	Gaps:	41/162 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 KPQHSYIGLIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRS 193
            ||.:|||.||||||..:.:.:|.|..||::|.:.:|::|.....|:|||||||:|||||:|..|.
Human    53 KPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPRE 117

  Fly   194 AN--GKGHYWAIHPANMED-FRKGDFRRRKAQRKVRKHMGLS-----VDDASTDSPS-------- 242
            |.  |||:|||:.| |.|| |..|.|.||   ||..|...||     :.||:..:.:
Human   118 AGRPGKGNYWALDP-NAEDMFESGSFLRR---RKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAA 178

  Fly   243 -----------PP----------PLDLTTPPP 253
                       ||          |..|..|||
Human   179 AIFPGAVPAARPPYPGAVYAGYAPPSLAAPPP 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	45/86 (52%)
FOXE1	NP_004464.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	19..51
FOXE1	NP_004464.2	FH	53..141	CDD:214627	45/88 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820