DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fd102C and FOXJ1

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001445.2	Gene:	FOXJ1 / 2302	HGNCID:	3816	Length:	421	Species:	Homo sapiens

Alignment Length:	248	Identity:	79/248 - (31%)
Similarity:	105/248 - (42%)	Gaps:	55/248 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 PLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTGGSGASAPWLHLSPYGHHG-SGS 100
            |.|......|...::|..|: ||.:: .||.:....|. |||            .|:|:|. .||
Human    19 PEGGLEEPDALDDSLTSLQW-LQEFS-ILNAKAPALPP-GGT------------DPHGYHQVPGS 68

  Fly   101 LPSVNRMAALSTISLFPQTQRIFQPEEP-----------------------------KPQHSYIG 136
            ....:.:||.......|.|     |.:|                             ||.:||..
Human    69 AAPGSPLAADPACLGQPHT-----PGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYAT 128

  Fly   137 LIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSAN--GKGH 199
            ||.||:.:|...|:.||.||::|.||:.|||...|.|:||||||||||.||||..|..:  |||.
Human   129 LICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGG 193

  Fly   200 YWAIHPANMEDFRKGDFRRRKAQRKVRKHMGLSVDDASTDS--PSPPPLDLTT 250
            :|.|.|...|....|.|::|:.. .|..|...:...|...|  |...||.:.|
Human   194 FWRIDPQYAERLLSGAFKKRRLP-PVHIHPAFARQAAQEPSAVPRAGPLTVNT 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	44/85 (52%)
FOXJ1	NP_001445.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34		3/14 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	48..116		15/85 (18%)
		Forkhead	121..205	CDD:306709	44/83 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	261..302
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270467at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2114
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850