DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fd102C and Foxf2

DIOPT Version :9

Sequence 1:	NP_651951.1	Gene:	fd102C / 43843	FlyBaseID:	FBgn0039937	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_034355.2	Gene:	Foxf2 / 14238	MGIID:	1347479	Length:	446	Species:	Mus musculus

Alignment Length:	257	Identity:	86/257 - (33%)
Similarity:	109/257 - (42%)	Gaps:	69/257 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 CPQYGGTGGSGASAPWLHLSPYGHHGSGSLPSVNRMAALSTISLFPQTQRIFQPEEPKPQHSYIG 136
            |.....:||:||             |||.....              |..:.:||  ||.:|||.
Mouse    72 CKSAASSGGAGA-------------GSGGTKKA--------------TSGLRRPE--KPPYSYIA 107

  Fly   137 LIAMAILSSTDMKLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIK--SGRSANGKGH 199
            ||.|||.||...:|.||:|||::...:|:||....||:||:|||||||:||||  .|....||||
Mouse   108 LIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH 172

  Fly   200 YWAIHPANMEDFRKGDFR------RRKAQ------RKVRKHMGLSVDDASTDSPSPPPLDLTTPP 252
            ||.|.||:...|.:|.||      |||.|      .:|...:|...      |..|...|...||
Mouse   173 YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYHRVVSGLGFGA------SLLPQGFDFQAPP 231

  Fly   253 P-------PSSQSALQLSALGY-----------PYHQHYIGQFFNRSSAPGMTHY-SPPDPA 295
            .       ......|.:...||           |:|.|: ....:.|..||.|:. |.|.||
Mouse   232 SAPLGCHGQGGYGGLDMMPAGYDTGAGAPGHAHPHHLHH-HHVPHMSPNPGSTYMASCPVPA 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	Forkhead	129..213	CDD:278670	47/85 (55%)
Foxf2	NP_034355.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..97		9/51 (18%)
		FH	100..188	CDD:214627	47/87 (54%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	257..278		3/21 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	304..325
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	340..371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000010
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810