Protein Alignment fd102C and FOXN4

DIOPT Version :10

• Sequence 1: NP_651951.1
• Gene: fd102C / 43843
• FlyBaseID: FBgn0039937
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_011536224.1
• Gene: FOXN4 / 121643
• HGNCID: 21399
• Length: 518
• Species: Homo sapiens
• Alignment Length: 530
• Identity: 125/530 - (23%)
• Similarity: 186/530 - (35%)
• Gaps: 180/530 - (33%)

  Fly    20 TSSRDSNVPKPSLPNIYPLGTTRTSQAQSTTMTLEQYRLQLYNYALNIERLRCPQYGGTGGSGAS 84
            |..|||.:.:      :|:|...:|..|...        .||:.|..      ||:....|:...
Human   114 TGHRDSQMSQ------FPVGGQPSSGLQDPP--------HLYSPATQ------PQFPLPPGAQQC 158

  Fly    85 AP-WLHLSPYGHHGSGSLPSVNRMAALSTISLFPQTQRIFQPEEPKPQHSYIGLIAMAILSSTDM 148
            .| .|:..|:|.......|.|   |..|:..|.|:       ..|||.:||..|||||:.:|...
Human   159 PPVGLYGPPFGVRPPYPQPHV---AVHSSQELHPK-------HYPKPIYSYSCLIAMALKNSKTG 213

  Fly   149 KLVLSDIYQYILDNYPYFRSRGPGWRNSIRHNLSLNDCFIKSGRSANG---KGHYWAIHPANMED 210
            .|.:|:||.::.:::|||::...||:||:|||||||.||.|.....:|   ||..||::.|.::.
Human   214 SLPVSEIYSFMKEHFPYFKTAPDGWKNSVRHNLSLNKCFEKVENKMSGSSRKGCLWALNLARIDK 278

  Fly   211 FRKGDFR-RRKAQRKVRKHMGLSVDDASTDSPSPPPLD-LTTPPPPSSQSALQLSALGYPYHQHY 273
            ..:...: :||....:.:.|.           :|..|| |.:..|.|.:..      |.|
Human   279 MEEEMHKWKRKDLAAIHRSMA-----------NPEELDKLISDRPESCRRP------GKP----- 321

  Fly   274 IGQFFNRSSAPGMTHYS--------------PPDPALLMQRQEANNLDQTIQPTQLQ-QPHSHHQ 323
                 ....||.:||.:              ||.|.:.:..|..        |...| ||.:|
Human   322 -----GEPEAPVLTHATTVAVAHGCLAVSQLPPQPLMTLSLQSV--------PLHHQVQPQAH-- 371

  Fly   324 HFAYINSTTTTTIANMFSQTRKRQFDVASLLAPDVQIVDIVSEDQESSVTPTTSA---RTTTQTH 385
                                          ||||         ....:.||...|   .:.:...
Human   372 ------------------------------LAPD---------SPAPAQTPPLHALPDLSPSPLP 397

  Fly   386 HTVITKQTIHREVVLGLEKPVQDADIDADIDVEVNVDVVDDSIIPDTDSYTDGE--DRKKTRGTL 448
            |..:.:            .||...:|..|::.|  ||.:|.||:   |....|.  :..|..|
Human   398 HPAMGR------------APVDFINISTDMNTE--VDALDPSIM---DFALQGNLWEEMKDEG-- 443

  Fly   449 KQIFSIEDNNSYLIDGRLSSFDADP-------------DHDPDHDPEDLEQHN----FSIASSAA 496
               ||::         .|.:|...|             ....|....||:...    :|...|.|
Human   444 ---FSLD---------TLGAFADSPLGCDLGASGLTPASGGSDQSFPDLQVTGLYTAYSTPDSVA 496

  Fly   497 RSLGSSSSQH 506
            .|..|||||:
Human   497 ASGTSSSSQY 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fd102C	NP_651951.1	FH_FOXQ2-like	129..223	CDD:410809	39/97 (40%)
FOXN4	XP_011536224.1	PABP-1234	<56..219	CDD:130689	36/134 (27%)
		FH_FOXN4	189..294	CDD:410831	41/111 (37%)
		FAM75	318..>398	CDD:464237	22/144 (15%)