DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gyf and AT1G27430

DIOPT Version :9

Sequence 1:	NP_001162827.1	Gene:	Gyf / 43842	FlyBaseID:	FBgn0039936	Length:	1574	Species:	Drosophila melanogaster
Sequence 2:	NP_174063.4	Gene:	AT1G27430 / 839633	AraportID:	AT1G27430	Length:	1492	Species:	Arabidopsis thaliana

Alignment Length:	1713	Identity:	329/1713 - (19%)
Similarity:	559/1713 - (32%)	Gaps:	510/1713 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 TPSSEEDINQNS-----LGNNSRP----AWLQRSPSGFGSASRGSGRGGTVDRGRMRGKSAYHPI 152
            |.|||..::..|     :||.|.|    ||...:|.......:......|..|.|..
plant    39 TKSSEYKMDVRSPTPVPMGNPSDPNPKDAWRLDAPEDKKDWKKIVHENETSRRWREE-------- 95

  Fly   153 YQRPSGLYDESLSVISKAERTWSDRNGTGDSAATTTSTSGSGALD-WNGTPSSS----PRKDYSN 212
             :|.:||..     ..|.:|..::|.....|:..|.....:.|.| ||...|.:    ||:|...
plant    96 -ERETGLLG-----ARKVDRRKTERRIDSVSSRETGDIKNAAASDRWNDVNSRAAVHEPRRDNKW 154

  Fly   213 NHR----NLENWRRTRNEDGSGD--GPSSSGSMSGPDIAGWRSGVVGGSTNAGFGTNSHRWGRST 271
            :.|    :.|...|....|.:.|  .|.|.......::                        |:|
plant   155 SSRWGPDDKEKEARCEKVDINKDKEEPQSESQSVVSNV------------------------RAT 195

  Fly   272 SWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVNN 336
            |.||.| :.|......|..|.....|:.|.....|...|.|||      |.|.       :||..
plant   196 SERDSD-TRDKWRPRHRMESQSGGPSSYRAAPGFGLDRGRAEG------PNLG-------FTVGR 246

  Fly   337 AAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKS-- 399
            ........             |.|....||   .:.|.|:   ....:.|.||.|...|...|
plant   247 GRASTIGR-------------GSSTSLIGA---GSALSPV---FRYPRGKLLDMYRKQKPDSSLG 292

  Fly   400 KDLSDPDSGNDITPETSLTKDTNTTAVQEEVESSL----------SPISSTTTKEVIHGD--ISD 452
            :.|::.|....|| :.:|.:.....|...|.|::|          |.:.:::.:|.:.|:  :..
plant   293 RILTEMDEVASIT-QVALIEPLAFIAPDAEEEANLNGIWKGRIISSEVYTSSGEESLGGNSLLKC 356

  Fly   453 RIKEVAD-EVEKLIM----DDDHKISSNQS----QHQNHDGFTAALPRMADIEINVKPSVTAVHR 508
            ||.|..: :|:..::    .|:..:.:|.|    .|....|..:::||:..:......|..|.::
plant   357 RIPESGETKVDGALLGFMNGDNGSMKNNDSGLLGSHNGGLGAASSVPRLNSVASESYGSGGAGYQ 421

  Fly   509 QA-PSTMPIQITPTITDVAPPSHAVV-SF--------SDHETMQHHNMHHLP--QFPMIPTPHII 561
            .: .|...::...|.:.|...|.:|| ||        ...:|...|:...:|  :|
plant   422 LSHGSPEAVRSVFTKSSVLDGSESVVGSFEQAYTGKLQQPDTEVDHSEGAMPPEEF--------- 477

  Fly   562 TPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYS---DNRFRPLGELIKFCHGN 623
                  |:.|.|||..:||||...::..|:..|:|..:|.||..|   ...|:.||.::.:....
plant   478 ------LFLYIDPQGVIQGPFIGSDIISWFEQGFFGTDLQVRLASAPEGTPFQDLGRVMSYIKAE 536

  Fly   624 MPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVEQQLQQQRDEQLKANVT 688
            .  .|:|:.....|||                                        :..||||..
plant   537 S--VHAHISDQKSELE----------------------------------------ETSLKANSE 559

  Fly   689 ATAEALRAAIKGSFGGNSIGNTSHLLT---MRFQML-----QDQYIQHQEYQILAE--LSKNECF 743
            |         .||....:..|.|..||   ..|.:.     ||.:.:..|.::...  .::::.|
plant   560 A---------GGSVAHVAESNDSSSLTGISRSFSVYNNPSGQDNFQRKSESEVYGRPPHAEDQSF 615

  Fly   744 QRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLN-----PVAGRQLYRAVVEHAKKDQQH 803
            ...||.::|.|...:.::.|....:.|...:.::|...:     ||   ::..|...:..:::.|
plant   616 LDFSAQDEEIVFPGRARVSGYASSVKSSTSMHDALMEFSGHSDIPV---EVTTAATRNQNENKLH 677

  Fly   804 IFANTEQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNEL 868
            .|                                 |.|.|.    ::||:    ...|.:|....
plant   678 PF---------------------------------GVLWSE----LEGGS----TPVNPLPNRSS 701

  Fly   869 DLINEYNLRMLLRGQPTSTQQQPPALTNSATENLPG---VDFLTETQLLERQNLMIPIWLPPNNN 930
            ..:.|.:..  :..:|.::::......|.:.:.|.|   ..|..|:......:     .||.|.:
plant   702 GAMGEPSCS--IENRPINSRRNSQIDPNISLDALSGNRMSQFEHESNFFNHGD-----QLPSNQH 759

  Fly   931 KQQ--ETDQQWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSG 993
            .||  :.....:.:...|..|.....|  :..:.|::.:|:..:......:| :::.| .|::..
plant   760 HQQHFQNRDMLSHLHIGDQDLEHLITL--QLQQQQKIQMQQQQKIQLQQQQK-IQLQQ-HQLEQE 820

  Fly   994 NVVNHTALEELDQSPQNLKGSHNQKIVKSLVSDIQ--QNHN-------EELNSHQHQVKQANKQN 1049
            :.::...|:|..||  :.:..|.|:|::....|.:  |:|:       :::...|..:.:..|.:
plant   821 HQLHQKLLQEQQQS--HARQLHFQQILQGQTPDTRFGQSHDFPRSNSVDQMLLEQQMLNELQKSS 883

  Fly  1050 LNTKQNAA----QSALKPIN--NENDRKREQTEEKKRQREERKRQQLEDDKRRALNESEEQTRQI 1108
            .:..||.|    |.|.....  .....:||..|    |....:.|.....|:....:.:.|..|:
plant   884 GHPSQNFAPYIEQHAAGNFGRFTHEGHQRELLE----QLFSTQMQSQYGQKQSQYGQMQSQHGQL 944

  Fly  1109 QEEKERQQQIQAQRRKALLGNVHSLSVQNGM-SGTLASAQ--------SKKNDDAKTAEPQVSSR 1164
            |.|..|..:.|..:::.|      :.:.||: ..||...|        |..:|......|.:...
plant   945 QSEPIRSLEYQLLQQEQL------MQLANGVRHNTLLEEQRHIDPLWPSDHSDQLLRTHPGIHRS 1003

  Fly  1165 LPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQRHQELLDKQLRANAAAAA-------- 1221
            ..|....|..|..|   :..|...:......|.|...||...|||:..|....:|:.
plant  1004 HSSAGFRPLDFHQQ---QQRPHFEDQFSQLERNRSYQQQLRLELLEHGLPFERSASGLNLDAVNG 1065

  Fly  1222 -------EANDALLKWQ-------STPASA---PVMSLAE-----IQAEEAR------RLANDLV 1258
                   |..||....|       |||..:   |.:.|.|     ::..|.|      :||.|..
plant  1066 LGLSQGLELRDATAHMQSSGRLGNSTPGFSHQNPRIPLGESHFSHLEPTEGRWSGADTQLAGDWA 1130

  Fly  1259 DRQRRR---------------------------------------ELEH----HQQAP------- 1273
            :.|.||                                       ||.|    ||.|.
plant  1131 ESQFRRSNMDTEHDKMRSEIRRLGEDPNSWMVGGSTDDKSKQLFMELLHQRPGHQSAESPNMNRG 1195

  Fly  1274 ----------LSSAVLVTSATSNIWGNAN--KAWSSSAAQSLSLKTSSGTGLWDEPNPLGSNGSG 1326
                      |:..:......|:..||.|  .|:...:.....:....|.|     |.:||....
plant  1196 YPYDRMVPSGLTPGIQTLGGLSDHGGNQNVSSAFGDRSFSDEQVNRVPGYG-----NNMGSLHHN 1255

  Fly  1327 TSGTSSVTAAAVLAGGLNSANKSTLQAQNKSSALFASPRNLRKSQTLPALSNPEKSNKNGPGQRP 1391
            :|          |..|:..|.:||   ||::.| |::...:.|.      :|...:..|.|   |
plant  1256 SS----------LLSGIIDAGRST---QNETQA-FSNMFGMNKD------ANDINTWNNVP---P 1297

  Fly  1392 EKQKLAQTRSKGAAVSIEEKDR-------------ERKLNAKSQQSSTDQAISKVNEYENEFTSW 1443
            :.:.:      |..:|.:.:||             |..:....||||.:  ||  :.|.:.
plant  1298 KNEGM------GRMMSYDAQDRMGKQAVLDSLIQEELPVGTPGQQSSFN--IS--DRYSDN---- 1348

  Fly  1444 CIKSLDNMSAKVDVPT----------------------FVAFLQDLEAPYEVKDYVRIYLG---- 1482
             :...|....::.||:                      .:..:.|..:......|..|..|
plant  1349 -LVGEDRRKDRLVVPSHGQNSVLLKRPPSSHSSSSHEGLLERMSDTASRAAASSYSGIEGGVRRE 1412

  Fly  1483 ----DGKDSLDFAKQFLERRSKYKSLQRAQKAHNDDMCKPAPAITPSANDYADSKNKQKKIKKNK 1543
                ..|.|...|..|.|...|..|:::......|            |.:.:.....:||.||.:
plant  1413 SGAAGNKGSTSEAASFSEMLKKSNSMKKVAAESTD------------ATEGSKGGGGKKKGKKGR 1465

  Fly  1544 MTKMDARILGFSVTAAEGRINVG 1566
              ::|..:|||.||:  .||.:|
plant  1466 --QIDPALLGFKVTS--NRILMG 1484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyf	NP_001162827.1	GYF	566..621	CDD:238027	19/57 (33%)
Gyf	NP_001162827.1	PKK	998..1112	CDD:289257	26/128 (20%)
AT1G27430	NP_174063.4	GYF	477..532	CDD:214666	20/69 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	45	1.000	Domainoid score	I4630
eggNOG	1	0.900	-	-		E1_KOG1862
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900