Protein Alignment Gyf and mpd2

DIOPT Version :10

• Sequence 1: NP_001162827.1
• Gene: Gyf / 43842
• FlyBaseID: FBgn0039936
• Length: 1574
• Species: Drosophila melanogaster
• Sequence 2: NP_594756.1
• Gene: mpd2 / 2543445
• PomBaseID: SPAC4F10.13C
• Length: 992
• Species: Schizosaccharomyces pombe
• Alignment Length: 1342
• Identity: 257/1342 - (19%)
• Similarity: 442/1342 - (32%)
• Gaps: 458/1342 - (34%)

  Fly    40 HNLGNNTAASASRNLFPEYRYGREEMLSLFDRNCLLPQILPSF-KKLFVEKVQCPLA--LTPSSE 101
            |...||:::|.: ..||:                     |.|| |......|..|.:  :.||..
pombe    21 HKKANNSSSSTT-GAFPQ---------------------LTSFTKPTATNGVDSPTSSHIDPSVS 63

  Fly   102 EDI-NQNSLGNNSRPAW---------LQRSPSGFGSASRGSGRGGTVDRGRMRGKSAY-HPIY-Q 154
            ..: :|..|...|...|         ..::|:  .|::..|.....|..|   |...| :|:. .
pombe    64 AKLDSQRKLSLKSGNMWDSLNAPSELTSKNPT--VSSTTSSANPAIVSNG---GSPFYKNPVVAN 123

  Fly   155 RPSGLYDESLSVISKAERTWSDRNGTGDSA-----------ATTTSTSGSGALDWNGTPSSSPRK 208
            .||..:|.|.::.:......|..|...:..           ::.:.|:|          ::||:.
pombe   124 NPSSTFDMSTNLFNSKNANTSFTNAFSNEGISPGFLRDCFPSSNSITTG----------TASPKL 178

  Fly   209 DYSNNHRNLENWRRTRNEDGSGDGPSS-SGSMSGPDIAGWRSGVVGGSTNAGFGT--NSHRWGRS 270
            ....||.|.....|:         ||| |.|.|          .|.|:.|.|.||  ...|.| |
pombe   179 GSPFNHINRPVLDRS---------PSSFSQSRS----------AVSGNMNPGVGTLQQPQRAG-S 223

  Fly   271 TSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKGSGIGAAEGVGSISHPRLSSSKISQLWTVN 335
            .::.|.:.|..|....:.::::..|.|.:...:             |..||..||:.||...|.:
pombe   224 DTFPDLNTSSSNQPGGEPNVASANTHSLEILSS-------------SAYHPSGSSNGISAGLTQS 275

  Fly   336 NAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTDLKPIKSSHNTLKTKSLDSYDDVKRPKSK 400
            .|:.|...:||                      .|....|::...:...|.|     :|....|.
pombe   276 VASPVGQVDNL----------------------ADFSQSPLRRGPSRFPTNS-----NVPVGNSM 313

  Fly   401 DLSDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPISSTTTKEVIHGDISDRIKEVADEVEKLI 465
            .:.|.||..:|..:.:..|    .:::|.....::|
pombe   314 SIRDTDSPLNILVDKAKAK----ASIKENASQPVAP----------------------------- 345

  Fly   466 MDDDHKISSNQSQHQNHDGFTAALPRMADIEINVKPSVTAVHRQAPSTMPIQITPTITDVAPPSH 530
                   |::|.:|...:...||:                    :|||
pombe   346 -------SASQREHSAVNSPAAAM--------------------SPST----------------- 366

  Fly   531 AVVSFSDHETMQHHNMHHLPQFPMIPTPHIITPNLNELWFYRDPQANVQGPFSAVEMTEWYRAGY 595
              ..||.....||             ...:|.|.|.. |.|:|||.||||||:.|:|.:||||||
pombe   367 --AMFSSEAFPQH-------------LASLIPPALLH-WLYKDPQNNVQGPFTGVDMHQWYRAGY 415

  Fly   596 FNENLFVRRYSDNRFRPLGELIKFCHGNM--PFTHSHLLP-SPIELENIPVGQIPAPLTASLSIT 657
            |...|.::|..:..:..|...|:.. ||.  ||    |:| ||:.::|           ||.:.
pombe   416 FPLGLPIKRLEEEEYYSLAFFIRQV-GNQLEPF----LVPLSPVTVQN-----------ASWNA- 463

  Fly   658 PHKPSPIPIALSVVEQQLQQQRDEQLKANVTATAEALRAAIKGSFGGNS----IGNTSHLLTMRF 718
              :.:.:|:: :.:.:..:|.|                       |||.    ..:|:.:..:|
pombe   464 --QGTDLPLS-NYLPESSEQNR-----------------------GGNKHLELYPSTAEVSNVR- 501

  Fly   719 QMLQDQYIQHQEYQILAELSKN---ECFQRLSAVEQETVVRRKVQLLGLPE-------------Y 767
               .|:    .:...|:|:|.|   ||......|.:::..:::...||..:             :
pombe   502 ---NDE----SKANSLSEISYNQQSECRSSELNVNEDSANQKEESALGTSDNSDMYEKENTPIHH 559

  Fly   768 LISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANTEQQRSVGNLLDANNFILNAQIMIQ 832
            ..|||.||..|..:          ::.|..|:::......|.:.:.:...:...:...:.:|.:.
pombe   560 NESLNQLSKDLGSI----------SLSEETKQEKPSKLKETVESKRLSTGVQKQSPAASKEIPVT 614

  Fly   833 QSQQEVGPLVSSVDCIMQGGTAADLNKPN---EIPRNELDLINEYNLRMLLRGQPTSTQQQPPAL 894
            ...|...|                  ||:   .:|...|..::|           |.:::    :
pombe   615 SGSQTTAP------------------KPSPWKSLPPKHLPSLDE-----------TISRE----M 646

  Fly   895 TNSATENLPGVDFLTETQLLERQNLMIPIWLPPNNNKQQETDQQWAEMSNADASLWETANLNEER 959
            :.:::|.||.|         |:.|...|....|:.:|   |...||::|:...|:.:.....|::
pombe   647 SIASSEALPQV---------EKSNSDQPPVAIPSTSK---TGSPWAKVSDVSTSMAQEIQRMEKQ 699

  Fly   960 NEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSG------NVVNHTALEELDQSPQNLKGSHNQK 1018
            ||:   |..|.:....:.|..:.| |....:.||      :|:|..|     ..|..||    ..
pombe   700 NEN---LKSKVASNPVSQTSTNAK-ASTPALASGSIWGSPSVINAWA-----NKPAALK----SP 751

  Fly  1019 IVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNENDRKREQTEEKKRQRE 1083
            ::|..:...:...|::.:|......::|..|.||.:.||.|:...:.|........|.|
pombe   752 LIKKNIQQAELAQNKQQSSVTTASPRSNALNANTPKAAAPSSNVTMKNVTSILETSTFE------ 810

  Fly  1084 ERKRQQLEDDKRRALNESEEQTRQI---------QEEKERQQQIQAQRRKALLGNVHSLSVQNGM 1139
                              .|.|..:         |:....||..::..:               :
pombe   811 ------------------GEDTWSVVGPGGKIVNQQSPSAQQTTRSPSK---------------V 842

  Fly  1140 SGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQNSMRSAPGLAEIQKAERRERRADQQR 1204
            |.||.:..|:.:..:| .:..||....|.....|      ...|..||.|            ...
pombe   843 SATLNAGNSQASTSSK-LQQVVSMSGHSPDFLAW------CKISLKGLNE------------GVN 888

  Fly  1205 HQELLDKQLRANAAAAAEANDALLKWQSTPASAPVMSLAEIQAEEARRLANDLVDRQRRRELEHH 1269
            ::|.||..|...|....|..:.:.  .|..|::.:|......:|..||...||..:..::. .:.
pombe   889 YEEFLDMLLSLPAENNVETFEIIS--DSIYANSTIMDGRRFASEFTRRRIADLTGKDGQQS-NNK 950

  Fly  1270 QQAPLSSAVLVTSATSNIWGNANKAWSSSAAQSLSLKTSSGT 1311
            .|:.|              ||::.|||    |.:..|...||
pombe   951 SQSEL--------------GNSSGAWS----QVVRNKPKQGT 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyf	NP_001162827.1	GYF	569..613	CDD:460496	22/43 (51%)
		Mplasa_alph_rch	<931..>1113	CDD:275316	38/196 (19%)
mpd2	NP_594756.1	GYF	388..442	CDD:214666	24/55 (44%)