Protein Alignment Gyf and gigyf2

DIOPT Version :9

• Sequence 1: NP_001162827.1
• Gene: Gyf / 43842
• FlyBaseID: FBgn0039936
• Length: 1574
• Species: Drosophila melanogaster
• Sequence 2: XP_002933400.2
• Gene: gigyf2 / 100487831
• XenbaseID: XB-GENE-5870324
• Length: 1309
• Species: Xenopus tropicalis
• Alignment Length: 1719
• Identity: 387/1719 - (22%)
• Similarity: 641/1719 - (37%)
• Gaps: 564/1719 - (32%)

  Fly     2 TDSMKFGPEWLRNMSAEPSGSPSTYNVGNAAQNNSIGGHNLGNNTAASASRNLFPEYRYGREEML 66
            |.::.|||||||.:|:                    ||..:....:.:..:....::||||||||
 Frog     5 TQTLNFGPEWLRALSS--------------------GGSVISPPLSPALPKYKLADFRYGREEML 49

  Fly    67 SLFDRNCLLPQIL--PSFKKLFVEKVQCPLALTPSSEEDINQNSLGNNSRPA--WLQRSPSGFGS 127
            :|:.::..:|..|  ..|..:..::...||||.|.:||:....|:..||...  ...|..||.|.
 Frog    50 ALYVKDNKVPLDLLDKEFLPILNDEPLLPLALVPFTEEEQRNFSMSVNSAAVLRLTNRGSSGGGG 114

  Fly   128 ASRGS--GRGGTVDRGRMRGKSAYHPIYQRPSGLYDESLSVISKAER------TWSDRNGTGDS- 183
            ...|:  ||..:..|||.||:|.:   |||.   :||..|...:..|      :|.:|   ||.
 Frog   115 TVVGAPRGRSSSRGRGRGRGESGF---YQRS---FDEVESGFGRGAREMHRSQSWEER---GDRR 170

  Fly   184 -AATTTSTSGSGALDWNGTPSSSPRKDY----SNNHRNLENWRRTRNEDGSGDGPSSSGSMSGPD 243
             ...|.........:..||..:..:.::    |.|.|:|........|:|.|...:|:....|
 Frog   171 FEKPTRKEPVRPTFEEGGTAPAGRKHEFIRSESGNWRSLREEMNGEEEEGGGVWRASAPRRDG-- 233

  Fly   244 IAGWRSGVVGGSTNAGFGTNSHRWGRSTSWRDEDPSVDNAASLQRSISTVATLSTDRTGNNKG-S 307
             ..|||....|:             |.:.||:       ....:|..........|..|..:. |
 Frog   234 -ERWRSHSPDGA-------------RGSGWRE-------IPDRRRRFDYDLREREDERGYRRARS 277

  Fly   308 GIGAAEGVGSISHPRLSSSKISQLWTVNNAAGVDADENLPEWAIENPSKLGGSFDASGAFHGDTD 372
            |.|:||                           |..::||||.:::.....|:||:||||
 Frog   278 GSGSAE---------------------------DERDSLPEWCLDDAEDETGTFDSSGAF----- 310

  Fly   373 LKPIKSSHNTLKTKSLDSYDDVKRPKSKDLSDPDSGNDITPETSLTKDTNTTAVQEEVESSLSPI 437
                      |.:|..........|:.::|       |..|......::::...|.|......|:
 Frog   311 ----------LSSKPSKKVQKEPIPEEQEL-------DFRPSMDGADNSDSDGSQTEEAKETDPV 358

  Fly   438 SSTTTKEVIHGDISDRIKEVADEVEKLIMDDDHKISS------NQSQHQNHDGFTAALPRMA-DI 495
            .|.|..::.....:         |.:.....||:|.|      ..|:..|.   .||.|.:: ..
 Frog   359 QSRTDNDLSRNGYT---------VVQATSSPDHRIPSPVPRTDKTSETANQ---KAASPHLSCKT 411

  Fly   496 EINVK------PSVTAVHRQAPSTMPIQ-----ITPTITDVAPPSHAVVSFSDHETMQHHNMHHL 549
            ||:|:      |...:.|::..:::..|     .:|.|..  |||.|   ||.....:..:.|.:
 Frog   412 EIDVRSQSPSSPPTPSKHKEDAASLSHQGSQEKSSPCIPH--PPSPA---FSQRSPARQPDPHKV 471

  Fly   550 PQFPMIPTPHIITPNL------------------------------------------------- 565
            |....:|.|.:.||.:
 Frog   472 PAMSSVPVPQLDTPTVPAHSTVCAAPGMEPMPPEPDEEDGLEHLEQQAQQMVAYLQDGTLDDDRL 536

  Fly   566 ----------------NELWFYRDPQANVQGPFSAVEMTEWYRAGYFNENLFVRRYSDNRFRPLG 614
                            .:.|:|:|||..:|||||..||.|||:||||...|.:||..|:.|:.||
 Frog   537 LVKVLDQRVKGPSLDNQQKWYYKDPQGEIQGPFSNREMAEWYQAGYFPMTLLLRRVCDDAFQSLG 601

  Fly   615 ELIKFCHGNMPFTHSHLLPSPIELENIPVGQIPAPLTASLSITPHKPSPIPIALSVVE-QQLQQQ 678
            ::|| ..|.:||:                             ||    |.|..|..:: ::|.:|
 Frog   602 DIIK-KWGRVPFS-----------------------------TP----PTPTRLGDLDPERLSRQ 632

  Fly   679 RDEQLKANVTATAEALRAAIKGSFGGNSIGNTSHLLTMRFQMLQDQYIQHQEYQILAELSKNECF 743
            ::      :||                 :....||   |:|    |::..|:|.:||:..|
 Frog   633 QE------ITA-----------------LYQMHHL---RYQ----QFLFQQQYAVLAQQQK---- 663

  Fly   744 QRLSAVEQETVVRRKVQLLGLPEYLISLNGLSNSLSVLNPVAGRQLYRAVVEHAKKDQQHIFANT 808
            ..||:.:|:..:..:...:.:||:           :|:.|||     ||:             :.
 Frog   664 AALSSQQQQLPLPLQSLSMRIPEH-----------TVIPPVA-----RAL-------------SV 699

  Fly   809 EQQRSVGNLLDANNFILNAQIMIQQSQQEVGPLVSSVDCIMQGGTAADLNKPNEIPRNELDLINE 873
            ....|:..|                      |..::...:.:|.:..||  |.|
 Frog   700 PDSTSLWEL----------------------PPAAAQPAVWEGSSVWDL--PVE----------- 729

  Fly   874 YNLRMLLRGQPTSTQQQPPALTNSATENLPGVDFLTETQL-LERQNLMIPIWLPPNNNKQQETDQ 937
                              ||...:..|.|..::.:...:: .||:...:       ..||:|.:|
 Frog   730 ------------------PANQGTTREQLEQMEKVKAAKMEQERREAEL-------RAKQEEEEQ 769

  Fly   938 QWAEMSNADASLWETANLNEERNEDQQLLIQKSSEACFADTEKDVKIAQLFQVQSGNVVNHTALE 1002
            :..:         |.....:.|.|::||..:|..|.    ..:..::|...|::          |
 Frog   770 RRRQ---------EEEEERKRREEEEQLARRKQEET----LRRQKELALQKQME----------E 811

  Fly  1003 ELDQSPQNLKGSHNQKIVKSLVSDIQQNHNEELNSHQHQVKQANKQNLNTKQNAAQSALKPINNE 1067
            |..|..:.|:           :.:.::...||....:.::::..::....::...::..:....|
 Frog   812 EERQRKEELR-----------LLEERRRQEEERKRLEEEIRRQEEEKRRQEEERKRAEDEKRRRE 865

  Fly  1068 NDRKREQTEEKKRQREERKRQQ---------LEDDKRRALNE----SEEQTRQIQEEKERQQQIQ 1119
            .::|||  ||::|||||.:|:|         .|:..||.|.|    :||:.|:.:||.:||:::|
 Frog   866 EEKKRE--EEERRQREEIQRKQEEAARWAREEEEAARRLLEEARLKAEEEERKKREEAQRQKELQ 928

  Fly  1120 AQRRKALLGNVHSLSVQNGMSGTLASAQSKKNDDAKTAEPQVSSRLPSTSVAPWSFQLQ--NSMR 1182
            .||::              ....|...|.::..     :.....:|||:|.  |..|:.  .:.:
 Frog   929 RQRQQ--------------QQEALRRLQQQQQQ-----QQLAQMKLPSSST--WGQQVSPTTASQ 972

  Fly  1183 SAPGLAEIQKAERRERRADQQRHQELLDKQLR--ANAAAAAEANDALLKWQSTPASAPV---MSL 1242
            ||..||||||.|....|...|.||....::|:  .......:....:..|.|  .|.||   .||
 Frog   973 SALSLAEIQKLEEERERQQLQEHQRRQQQELKILQQQQQQQQQQQKIPGWGS--VSKPVGSTKSL 1035

  Fly  1243 AEIQAEEARRLANDLVDRQRRRELEHHQQAPLS-------SAVLVTSATSNIWGNANK----AWS 1296
            .|||.||||::..  ..:|..|....:...|::       |:..|..:.|::||:.|.    .||
 Frog  1036 LEIQQEEARQMQK--TQQQPVRNRPANISVPVAPVVNNHISSTSVAGSGSSVWGSLNNNLSPQWS 1098

  Fly  1297 SSAAQSLSLKT---SSGTGLWDEPNPLGSNGSGTSGTSSVTAAAVLAGGLNSANKSTLQAQNKSS 1358
            |.:..|:...|   .|..|.||:            ....||.....:...|:|:||.
 Frog  1099 SDSMSSIWSSTEVKGSSVGFWDD------------AVKEVTPRNATSKNKNTASKSA-------- 1143

  Fly  1359 ALFASPRNLRKSQTLPALSNPEKSNKNGPGQRPEKQKLAQTRSKGAAVSIEEKDRERKLNAKSQQ 1423
                                       ||..|..|:             :|::::..:|
 Frog  1144 ---------------------------GPNSRQSKK-------------VEQEEKLLRL------ 1162

  Fly  1424 SSTDQAISKVNEYENEFTSWCIKSLD--NMSAKVDVPTFVAFLQDLEAPYEVKDYVRIYLGDGKD 1486
                  ....|:.::.||.||.::|.  |.:..:||||||:||:::|:||||.||||.||||..:
 Frog  1163 ------FQGANKCQDGFTQWCEQTLHAINTAHSLDVPTFVSFLREVESPYEVHDYVRAYLGDTPE 1221

  Fly  1487 SLDFAKQFLERRSKYKSLQRAQKAH-NDDM----CKPAPAIT-PSANDYADSKNKQKKIKKNKMT 1545
            :.||:|||:|||:|    |:|.:.| ..|:    |:.:.|.: .:|.:.|....::|  ||.||.
 Frog  1222 AKDFSKQFIERRTK----QKASQQHPQQDVAWVTCQTSQANSQQTALEVAQCAGRKK--KKQKMV 1280

  Fly  1546 KMDARILGFSVTAAEGRINVG----IRDY 1570
            :.|..:|||||.|:..|:|:|    :.||
 Frog  1281 RADPSLLGFSVNASSERLNMGEIETVEDY 1309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyf	NP_001162827.1	GYF	566..621	CDD:238027	28/54 (52%)
		PKK	998..1112	CDD:289257	28/126 (22%)
gigyf2	XP_002933400.2	GYF	556..600	CDD:366985	24/43 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I3770
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	297	1.000	Inparanoid score	I2673
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001680
OrthoInspector	1	1.000	-	-		otm47767
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2990
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	6.050