DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment unc-13 and AT5G12970

DIOPT Version :9

Sequence 1:	NP_001245427.1	Gene:	unc-13 / 43841	FlyBaseID:	FBgn0025726	Length:	3186	Species:	Drosophila melanogaster
Sequence 2:	NP_196801.1	Gene:	AT5G12970 / 831137	AraportID:	AT5G12970	Length:	769	Species:	Arabidopsis thaliana

Alignment Length:	246	Identity:	62/246 - (25%)
Similarity:	101/246 - (41%)	Gaps:	56/246 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  2114 RMKQREREKPEIFELIRAVF----SVEEKSHAGHMKA----------VKQSVLDGTSKWSAKIAI 2164
            |::.|...|.: .||:.||:    :.|..|.|.|..|          ::..|......|  .:.:
plant   144 RLEDRHGRKVK-GELMLAVWMGTQADEAFSDAWHSDAATVGPEGVTHIRSKVYLSPKLW--YVRV 205

  Fly  2165 TVICAQGLIAKDKSGTSDPYVTVQVSKVKKRTR-TMPQELNPVWNEKFHFECHNSSDRIKVRVWD 2228
            .||.||.||..||:...:.||...:.....||| :..:.|||:|||...|        :....::
plant   206 NVIEAQDLIPHDKTKFPEVYVKAMLGNQTLRTRISQTKTLNPMWNEDLMF--------VVAEPFE 262

  Fly  2229 EDNDLKSKLRQKLTRESDDFLGQTIIEVRTLSGEMD------VWYNLEKRT----DKSAVSGAIR 2283
            |  .|...:..::....|:.||:..|.::.:...:|      .|:||||..    ::..:..|.|
plant   263 E--ALILAVEDRVAPNKDETLGRCAIPLQNVQRRLDHRPLNSRWFNLEKHIMVEGEQKEIKFASR 325

  Fly  2284 LHISVEIKGEEKVAPYHVQYTCLHENLFHYLCEENTGMVKLPTQKGDDAWK 2334
            :|:.:.::|     .|||    |.|:. ||..:..      ||.|  ..||
plant   326 IHLRIFLEG-----GYHV----LDEST-HYSSDLR------PTAK--QLWK 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unc-13	NP_001245427.1	C1	2038..2087	CDD:237996
		C2B_Munc13	2160..2286	CDD:175993	34/136 (25%)
		DUF1041	2477..2584	CDD:283860
		Membr_traf_MHD	2832..2992	CDD:287505
		C2C_Munc13	3032..3152	CDD:176041
AT5G12970	NP_196801.1	C2B_MCTP_PRT_plant	41..165	CDD:176024	7/21 (33%)
		C2C_MCTP_PRT_plant	202..351	CDD:175986	43/174 (25%)
		C2D_MCTP_PRT_plant	363..486	CDD:176025
		PRT_C	614..769	CDD:285560
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D234298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920