DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment unc-13 and AT3G03680

DIOPT Version :9

Sequence 1:	NP_001245427.1	Gene:	unc-13 / 43841	FlyBaseID:	FBgn0025726	Length:	3186	Species:	Drosophila melanogaster
Sequence 2:	NP_187018.1	Gene:	AT3G03680 / 821190	AraportID:	AT3G03680	Length:	1017	Species:	Arabidopsis thaliana

Alignment Length:	194	Identity:	51/194 - (26%)
Similarity:	78/194 - (40%)	Gaps:	50/194 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  2161 KIAITVICAQGLIAKDKSGTSDPYVTVQVSKVKKRTRTMPQELNPVWNEKFHFECHNSSDRIKVR 2225
            |:.:.:..|:.|:.||..||:..|..|.....::||:|..::|||.|:||..|..|:      |.
plant     8 KLIVEICSARNLMPKDGQGTASAYAIVDFDGQRRRTKTKFRDLNPQWDEKLEFFVHD------VA 66

  Fly  2226 VWDED-------NDLKSKLRQKLTRESDDFLGQTII---EVRTLSGEMDVWYNLEKRTDKSAVSG 2280
            ...|:       ||       |.|.:...|||:..|   ...:...|..|:|.||||:
plant    67 TMGEEILEINLCND-------KKTGKRSTFLGKVKIAGSAFASAGSETLVYYPLEKRS------- 117

  Fly  2281 AIRLHISVEIKGEEKVAPYHVQYTCLHENLFHYLCEENTGMVKLPTQKGDDAWKLYFDEIPEEI 2344
                 :..:||||..:..|:|              :||.......|:...:| ....:|.|.||
plant   118 -----VFSQIKGEIGLKAYYV--------------DENPPAAPAATEPKPEA-AAATEEKPPEI 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
unc-13	NP_001245427.1	C1	2038..2087	CDD:237996
		C2B_Munc13	2160..2286	CDD:175993	37/134 (28%)
		DUF1041	2477..2584	CDD:283860
		Membr_traf_MHD	2832..2992	CDD:287505
		C2C_Munc13	3032..3152	CDD:176041
AT3G03680	NP_187018.1	C2	8..134	CDD:301316	43/164 (26%)
		C2B_MCTP_PRT_plant	282..407	CDD:176024
		C2C_MCTP_PRT_plant	440..593	CDD:175986
		C2D_MCTP_PRT_plant	605..733	CDD:176025
		PRT_C	861..1017	CDD:285560
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D234298at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920