DRSC - DRSC Integrative Ortholog Prediction Tool

DRSC/TRiP Functional Genomics Resources

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Protein Alignment mGluR and GLR3.3

DIOPT Version :10

Sequence 1:	NP_524639.2	Gene:	mGluR / 43838	FlyBaseID:	FBgn0019985	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	NP_174978.1	Gene:	GLR3.3 / 840859	AraportID:	AT1G42540	Length:	933	Species:	Arabidopsis thaliana

Alignment Length:	24	Identity:	8/24 - (33%)
Similarity:	10/24 - (41%)	Gaps:	8/24 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 SPMDRIWGIGL------SH--HDK 151
            :|..|.|..|.      ||  |:|
plant    71 TPYCRCWRSGTFPLCDGSHVKHNK 94

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mGluR	NP_524639.2	PBP1_mGluR_groupII	39..542	CDD:380598	8/24 (33%)
		NCD3G	556..605	CDD:462210
		7tmC_mGluRs_group2_3	625..876	CDD:320600
		TM helix 1	625..650	CDD:320600
		TM helix 2	662..683	CDD:320600
		TM helix 3	692..716	CDD:320600
		TM helix 4	738..758	CDD:320600
		TM helix 5	781..807	CDD:320600
		TM helix 6	815..838	CDD:320600
		TM helix 7	845..870	CDD:320600
GLR3.3	NP_174978.1	PBP1_GABAb_receptor_plant	30..423	CDD:380645	8/24 (33%)
GLR3.3	NP_174978.1	GluR_Plant	464..807	CDD:270404
Blue background indicates that the domain is not in the aligned region.

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