Protein Alignment mGluR and Gprc5b

DIOPT Version :9

• Sequence 1: NP_001259076.1
• Gene: mGluR / 43838
• FlyBaseID: FBgn0019985
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001182703.1
• Gene: Gprc5b / 64297
• MGIID: 1927596
• Length: 411
• Species: Mus musculus
• Alignment Length: 302
• Identity: 69/302 - (22%)
• Similarity: 136/302 - (45%)
• Gaps: 53/302 - (17%)

  Fly   595 TCKDCGPGLWPYADKLSCYALDIQYMK---WNSLFALIPMAIAIFGIALTSIVIVLFAKNHDTPL 656
            |.:.||..|.|            ||:.   .::::.::..|:|..|..:|.:::::....  .|.
Mouse    33 TSRGCGLDLLP------------QYVSLCDLDAIWGIVVEAVAGAGALITLLLMLILLVR--LPF 83

  Fly   657 VRASGRE----LSYTLLFGILVCYCNTFALIAKPTIGSCVLQRFGIGVGFSIIYSALLTKTNRIS 717
            ::...|:    |.:..|.|.|..:..|||.|.:.....|.::||..||.|::.:|.||::..|:.
Mouse    84 IKDKERKRPVCLHFLFLLGTLGLFGLTFAFIIQMDETICSIRRFLWGVLFALCFSCLLSQAWRVR 148

  Fly   718 RIFHSASKSAQRLKYISPQSQVVITTS--LIAIQVLITMIWMVVEPPGTRFYYPDRREVILKCKI 780
            |:....:         ||.|..:::.:  |:.:||:|...|:|:..         .|:....|..
Mouse   149 RLVRQGT---------SPASWQLVSLALCLMLVQVIIATEWLVLTV---------LRDTKPACAY 195

  Fly   781 QDMSFLFSQLYNMILITICTIYAIKTRKIPENFNESK----FIGFTMYTTCIIWLAFVPIYFGTG 841
            :.|.|:.:.:|:|:|:.|....::.|  :...|...|    ||..|.:.:.:||:.::.:|. .|
Mouse   196 EPMDFVMALIYDMVLLAITLAQSLFT--LCGKFKRWKVNGAFILVTTFLSALIWVVWMTMYL-FG 257

  Fly   842 NSYEVQ-----TTTLCISISLSASVALVCLYSPKVYILVFHP 878
            ||...|     ..||.|:::.|..|.::....|:::..:..|
Mouse   258 NSLIKQGDAWSDPTLAITLAASGWVFVIFHAIPEIHYTLLPP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mGluR	NP_001259076.1	Periplasmic_Binding_Protein_Type_1	43..542	CDD:299141
		ANF_receptor	72..518	CDD:279440
		NCD3G	557..604	CDD:284890	3/8 (38%)
		7tm_3	638..873	CDD:278433	58/249 (23%)
Gprc5b	NP_001182703.1	7tm_3	<112..293	CDD:278433	49/201 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..381

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910