Protein Alignment 4E-T and ifet-1

DIOPT Version :10

• Sequence 1: NP_726618.3
• Gene: 4E-T / 43836
• FlyBaseID: FBgn0052016
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: NP_001369844.1
• Gene: ifet-1 / 175583
• WormBaseID: WBGene00004132
• Length: 761
• Species: Caenorhabditis elegans
• Alignment Length: 880
• Identity: 171/880 - (19%)
• Similarity: 273/880 - (31%)
• Gaps: 293/880 - (33%)

  Fly   201 CMSSSPTFSTSRQERRIGSGRLLPRSD---------------NWDYKNEKTVEASIENEKETSPN 250
            |..:......|.|.|...||...|..|               ||  :|..|..|.     :.:..
 Worm    91 CAGADENTGLSPQRRAFSSGCKAPTDDKGRDGEYERLGGHGKNW--RNGSTGGAD-----KFASR 148

  Fly   251 GSGSTSSLNQHNQSQH------------RSRTFSGRLVERVPEVTDRRFQYDSKKSFDRQGINNR 303
            |:....|..:.||.:.            |...|:.|..||:..
 Worm   149 GNDFKPSFQKGNQLERGTRGAEWKKDTTRGAKFAPRREERLTS---------------------- 191

  Fly   304 RISGKEPFSTQSRSKRGNSYLIHEEPEWFSAGPKSQLETIDLHGFEDLEKNEERSVTEDKNNQIQ 368
             :||.|..                 ||| :.||.:..:.|:|.||:     |.:.|...||.:.:
 Worm   192 -LSGSEKL-----------------PEW-ADGPTTMDDMIELRGFD-----EPKKVKNKKNPKEK 232

  Fly   369 QLDKNLDAQASKDEASMRNSNDSLNFREVIPSDEK------------KHTDENVVT-----SIQN 416
            :..:.:.|....:....|.|:..|...|  |.|:.            ..||:.:..     .||.
 Worm   233 KEKEAVKAPEPVECVGSRPSSTGLKTSE--PIDDPAIAYSSSGGGALPATDQELAALLGCLDIQK 295

  Fly   417 ST------DLGHPNKNKPIQMQPSQNPESEFNFDAFLNMHPLDNSVLSNDETGKSDSKGTSRFSR 475
            ::      |:...:|::    :.:........|.|..|..|..:::||:...|..::......:|
 Worm   296 TSRKIDGDDMAWAHKSE----ETAGGTSRLSRFFAKKNKSPELDAMLSSVGGGNDENVANPMLAR 356

  Fly   476 WFRQKEAANNNEFPGFRESHAQEKRGIPSVKDLEAQMIKVDMRTDLINPIAGSLCQTVQMEKPIA 540
            .|......||....|     |.:.:|...::|||..|       :...|...|..|....:..:.
 Worm   357 LFGHSGGDNNASSSG-----AGDIKGGMRLEDLEKGM-------ESKEPSKVSPLQDPSQQAQLL 409

  Fly   541 RDTEAFKKLLQQLGSQARQHH-----PCNDDCRTINLSNIANHVHLESKLHQKINDGH--LQQPE 598
            :..:.|.|  ||..|....||     |.|..      .....|:|     |..::.|.  :..|.
 Worm   410 QHLQKFAK--QQAESGQHIHHHRQPTPPNGG------PQHQQHLH-----HPMVHPGMQIIADPS 461

  Fly   599 LSVNVPTMPTSSHVFLQKRLEIQHLIQRLHCGDVSHDFLEKELDNPSTPAATKDVIATVLNEYSH 663
            |..:....|...:.:::.:|:                    |..|.:..|.....:...|:|...
 Worm   462 LLASFAQNPVILNAYVENQLQ--------------------EAVNAAIRANNGQQLPPQLHEQLR 506

  Fly   664 --SKRNPVVTGDPNIFTQQSFL-------QPQSVHQHYSQELHSQNTANHTINQLISHGNSPTPL 719
              |.||       ..|.|...|       |.|::.||..|:.|.|:           .|.:|
 Worm   507 MASMRN-------KAFLQSQTLTFVSLQQQHQNIQQHQQQQQHHQH-----------KGRTP--- 550

  Fly   720 AFTPTSV---LRKMTADKDTQSPSTYCQNPQYHVHQQNAKQVGTRENVLEPQLTATMAVQPRMIL 781
            |..|.||   |:|.:::.|.:...|....|:.:....:|.......|.|:     .:.:|.
 Worm   551 AMIPASVQRQLQKSSSNADQKKEKTSQSPPESNQETSDAHNQSDAMNQLK-----KLHMQQ---- 606

  Fly   782 GGGNFAIGQNNQHLSPNMSQSRNQQVLKWTSGNMQMVHGKTFGRPILKGGLNSMPHSNSALPFTA 846
               |:|          ||.|:.|..| .|..|| .:|:|:             ..|....||...
 Worm   607 ---NYA----------NMVQAMNSGV-GWARGN-GVVNGQ-------------QQHPQQQLPPNV 643

  Fly   847 HKIEMQPIHQ----PHLQ------QQQHRFKAVQSVESNLNTESVHQNITSPVGWHQLYMQHQQQ 901
            ..:..|  ||    .||:      ||||...|                        ::....|||
 Worm   644 QMLMAQ--HQQAQMQHLKMMMSRAQQQHMLMA------------------------KIAQMQQQQ 682

  Fly   902 HHHTRQQLSQRVIYGEMHRQSNPQMSPPVPGFSDSSDSGNVIKANSLTSPSYQRDERISSPTNQL 966
            ......|..|    |..|.|.  |..|.||  |:.|..|          |.....|::.:.....
 Worm   683 AQMANMQERQ----GPSHNQQ--QHQPVVP--SELSQVG----------PIQTPLEKLLASVGVQ 729

  Fly   967 AQWFSPELLAKASAGKLPLLNVNQALSLEEFERSI 1001
            ...|:      .|..::|  :..:.:|||:.|:.:
 Worm   730 GSQFT------GSGDRIP--SSVRPMSLEDLEKQL 756

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
4E-T	NP_726618.3	EIF4E-T	10..736	CDD:371079	115/603 (19%)
ifet-1	NP_001369844.1	None