Protein Alignment 4E-T and LOC1275591

DIOPT Version :10

• Sequence 1: NP_726618.3
• Gene: 4E-T / 43836
• FlyBaseID: FBgn0052016
• Length: 1010
• Species: Drosophila melanogaster
• Sequence 2: XP_061513162.1
• Gene: LOC1275591 / 1275591
• VectorBaseID: AGAMI1_002868
• Length: 661
• Species: Anopheles gambiae
• Alignment Length: 858
• Identity: 168/858 - (19%)
• Similarity: 271/858 - (31%)
• Gaps: 378/858 - (44%)

  Fly   100 RFVPTDSLLISGEDKDKDALSHGQPYKLN----IIDHRSISSSHLMPAFAKRRFVISKG-----S 155
            :||.:|:...|        |.||:.|: |    :|:....|...|.||      ::|.|     .
Mosquito     3 KFVNSDTTTKS--------LRHGEQYE-NCSEMLIEPDMTSLEELDPA------ILSCGLPAIVL 52

  Fly   156 NSEESNEGINTCASKGKAASSPSRKGSELDTAETCLNFVQPDHDQCMSSSPTFSTSRQERR---- 216
            |:|:|            |||:                          |:.||.:|:...||
Mosquito    53 NAEDS------------AASA--------------------------SAVPTTTTTTTTRRTLRP 79

  Fly   217 --------IGSGRLLPRSDNWDYKNEKTVEASIENEKETSPNGSGSTSSLNQHNQSQHR--SRTF 271
                    :|:|..:.|         .||...:...|  ||......:::::...:|:.  |||.
Mosquito    80 SLMASFATVGAGANVIR---------YTVAHLLALRK--SPFAHRRPAAIDEPRTAQYPIWSRTG 133

  Fly   272 SGRLVERVPEVT----------DRRFQYDSKKSFDRQ---GINNRRISGKEPFSTQSRSKRGNSY 323
            .....:||..|:          |....| .:|..|||   |.|..|......||.::......||
Mosquito   134 FNHQPDRVRRVSGGGGGGGGDEDLSGAY-GRKGNDRQRDNGYNPPRFRRNHEFSNRNHHVIVKSY 197

  Fly   324 -------------------------------LIHEEPEWFSAGPKSQLETIDLHGF-EDLEKNEE 356
                                           :|.|||||.:|||.|:|:||:|.|| ||:.:|..
Mosquito   198 SGAAGGDPCAGGGHPLGGGGGVGGAMRLQDTIIEEEPEWVAAGPTSRLDTIELRGFDEDMSRNVA 262

  Fly   357 RSVTEDKNNQIQQLDKNLDAQASKDEASMRNS--NDSLNFREVIP--SDEKKH-------TDENV 410
            .|:                 :.|......|.:  ::.|::..|.|  ....||       ..|:|
Mosquito   263 ESL-----------------KTSPVGVKTRGAFFDELLHYEHVHPKHGGGAKHDLSGGPGDGESV 310

  Fly   411 VTSIQNSTDLGHPNKNKPIQMQPSQN-----------------------PESEFNFDAFLNMHPL 452
            |:...|.:.  .|.::.|.:...:.|                       ..|..|...|..:...
Mosquito   311 VSHSNNGSP--PPARSTPTKGDMNNNSMVGHGAHGRKASGGGSSGAAGCSSSGVNVSNFEELMKF 373

  Fly   453 DNSVLSNDETGKSDSKGTSRFSRWFRQKEAAN-----------NNEFPG---------------- 490
            | |:|.:    ..||..:||||:::|:....:           .:.:||
Mosquito   374 D-SILGD----SGDSNSSSRFSKYYRRGSGVSAGSSGAGGHHYQHHYPGQQQQQHHHVRFALERN 433

  Fly   491 ---FRESHAQEKRGIPSVKDLEAQMIKVDMRTDLINPIAGS----LCQTVQMEKPIARDTEAFKK 548
               :...|.|:::    .:..:|...::.: :.|.:|.||:    .........|.|.|.::|::
Mosquito   434 THHYNNGHQQQQQ----QQHRQAGSGRLPL-SALQHPPAGTGEPFFPGGASSTAPNAGDAKSFQR 493

  Fly   549 LLQQLGSQARQHHPCNDDCRTINLSNIANHVHLESKLHQKINDGHLQQPELSVNVPTMPTSSHVF 613
            ||:.|.:|                             :|::|..|.||..|.:
Mosquito   494 LLEMLAAQ-----------------------------NQRMNQQHQQQYLLQL------------ 517

  Fly   614 LQKRLEIQHLIQRLHCGDVSHDFLEK-ELDNPSTPAATKDVIATVLNEYSHSKRNPVVTGDPNIF 677
            ||...|.:.|.|.|         ::| .|||                           .|...|.
Mosquito   518 LQNCQETETLRQML---------MKKCTLDN---------------------------AGQQRIP 546

  Fly   678 TQQSFLQPQSVHQHYSQELHSQNTANHTINQLISHGNSPTPLAFTPTSVLRKMTADKDTQSPSTY 742
            ||...       |.::|.:..|                         ::|||..|::.
Mosquito   547 TQAEL-------QQHTQSIMKQ-------------------------ALLRKKIAEQS------- 572

  Fly   743 CQNPQYHVHQQNAKQVGTRENVLEPQLTATMAVQPRMILGGGNFAIGQNNQHLSPNMSQSRNQQV 807
                :|.:.||.      ::|..||    ..|||             |..|.:.||:  .|:..|
Mosquito   573 ----RYLLEQQQ------QQNGQEP----IPAVQ-------------QLIQSICPNV--QRSLSV 608

  Fly   808 LKWTSGNMQMVHG 820
            |...||:.|  ||
Mosquito   609 LAAGSGSGQ--HG 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
4E-T	NP_726618.3	EIF4E-T	10..736	CDD:371079	147/772 (19%)
LOC1275591	XP_061513162.1	None