DRSC/TRiP Functional Genomics Resources

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Protein Alignment fuss and Skor2

DIOPT Version :9

Sequence 1:NP_001162829.1 Gene:fuss / 43835 FlyBaseID:FBgn0039932 Length:770 Species:Drosophila melanogaster
Sequence 2:NP_001103213.1 Gene:Skor2 / 664805 MGIID:3645984 Length:1008 Species:Mus musculus


Alignment Length:308 Identity:187/308 - (60%)
Similarity:221/308 - (71%) Gaps:19/308 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 RSNHVSSVLLYGVQIVSLHIEGQERLCLAQISNTLLKQFSYNEIHNRRVALGITCVQCTPVQLEI 92
            :.|.|..|:|||:.||||.|:||||||||||||||||.|||||||||||||||||||||||||||
Mouse    37 KPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEI 101

  Fly    93 LRRAGAMPVSSRRCGMITRREAERLCKSFLGDNTPPRLPDDFAFNVQHKCAWGCRGSFLPSRYNS 157
            ||||||||:|||||||||:||||||||||||:|.||:|||:|||:|.|:|||||||||:|:||||
Mouse   102 LRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNS 166

  Fly   158 SRAKCIKCSYCGMFFSPNKFIFHSHRITTNDRYVQPDAANFNSWRRHMSLSGNDYDEKIIHAWED 222
            |||||||||||.|:|||||||||||| |.:.:|.|||||||||||||:.|:.....::::.||||
Mouse   167 SRAKCIKCSYCNMYFSPNKFIFHSHR-TPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWED 230

  Fly   223 VKAMFNGGTRKR-LVGSSINPR-SPGSPTQSTAVSSGVGSSSCGS-----------PTSFERDTN 274
            ||||||||:||| |...|.:|. .|.|..::.||::....:..|.           |........
Mouse   231 VKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPLA 295

  Fly   275 EVDG--KSGSSLPQRSQIDSQYNYGTVAAAAAVVGVTA---VAAATVG 317
            |:.|  .:....|:....|.......|.|||::....|   |||||.|
Mouse   296 ELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGG 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fussNP_001162829.1 Ski_Sno 25..123 CDD:280577 81/94 (86%)
c-SKI_SMAD_bind 135..228 CDD:198114 66/92 (72%)
Skor2NP_001103213.1 Ski_Sno 39..132 CDD:367087 81/92 (88%)
c-SKI_SMAD_bind 145..235 CDD:370119 64/90 (71%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 280..315 4/34 (12%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 514..927
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 169 1.000 Domainoid score I3797
eggNOG 1 0.900 - - E1_2C3ZR
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0003480
OrthoInspector 1 1.000 - - oto94840
orthoMCL 1 0.900 - - OOG6_106258
Panther 1 1.100 - - LDO PTHR10005
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R5040
SonicParanoid 1 1.000 - - X2371
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
109.890

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