Protein Alignment toy and PHO2

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_010177.1
• Gene: PHO2 / 851452
• SGDID: S000002264
• Length: 559
• Species: Saccharomyces cerevisiae
• Alignment Length: 619
• Identity: 111/619 - (17%)
• Similarity: 206/619 - (33%)
• Gaps: 224/619 - (36%)

  Fly   155 LASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDD 219
            |...::||.|||::..:                                      |...|.....
Yeast    22 LQHDQQQQQQQQHDQQH--------------------------------------NQQQQPQPQP 48

  Fly   220 VQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEF 284
            :|.:.|:        :.||..::..|..:::.|...|         :..||....|.:|.|:::|
Yeast    49 IQTQNLE--------HDHDQHTNDMSASSNASDSGPQ---------RPKRTRAKGEALDVLKRKF 96

  Fly   285 ERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQ-----RRSADTVDGSGRTST 344
            |....|.:..|::::|.||:||..:::||.|||||.|:::....:     .:|.|..:...|.||
Yeast    97 EINPTPSLVERKKISDLIGMPEKNVRIWFQNRRAKLRKKQHGSNKDTIPSSQSRDIANDYDRGST 161

  Fly   345 ANNPSGTTASSSV-------------ATSNNS--------------------------------- 363
            .||...||::||:             ..|||:
Yeast   162 DNNLVTTTSTSSIFHDEDLTFFDRIPLNSNNNYYFFDICSITVGSWNRMKSGALQRRNFQSIKEL 226

  Fly   364 ---TPGIVNSAIN--------VAERTS------SALVSNS---------LPEASNGPTVLGGE-- 400
               :|..:|:.::        ::::.|      ||:.:|:         |...:|....|..:
Yeast   227 RNLSPIKINNIMSNATDLMVLISKKNSEINYFFSAMANNTKILFRIFFPLSSVTNCSLTLETDDD 291

  Fly   401 -ANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPY 464
             .|:.:||.::            ||..|           ...:|.::|......|...:|:|...
Yeast   292 IINSNNTSDKN------------NSNTN-----------NDDDNDDNSNEDNDNSSEDKRNAKDN 333

  Fly   465 MFHDPLSL-GSPYVSAHHRNTA-------------CNPSAAHQQPPQHGVYTNSSP--------- 506
            .....|:: .||..:.:..|.|             |:..:..:|.....|..::.|
Yeast   334 FGELKLTVTRSPTFAVYFLNNAPDEDPNLNNQWSICDDFSEGRQVNDAFVGGSNIPHTLKGLQKS 398

  Fly   507 -----------------MPSSNTGVISAGVS----VPVQISTQNVSDLTGSNYWPRLQXSSIFGS 550
                             :|:.||.:.:|.|.    .|..::|.  |..|.||....|:.|..|
Yeast   399 LRFMNSLILDYKSSNEILPTINTAIPTAAVPQQNIAPPFLNTN--SSATDSNPNTNLEDSLFF-- 459

  Fly   551 PLDH-LSKATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTTCCSSRYLNMTFGA 614
              || |..::.......|.:....:..|:.::..:.||....|..:...:....:..:|:
Yeast   460 --DHDLLSSSITNTNNGQGSNNGRQASKDDTLNLLDTTVNSNNNHNANNEENHLAQEHLS----- 517

  Fly   615 GKDVDVVIGQGLIVSLTPHISGKP---ELFGSPN 645
             .|.|:|      .:...|:...|   ||..:|:
Yeast   518 -NDADIV------ANPNDHLLSLPTDSELPNTPD 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	38/168 (23%)
		Homeobox	269..322	CDD:395001	21/52 (40%)
PHO2	NP_010177.1	COG5576	53..183	CDD:227863	39/146 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I2756
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2514
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto100015
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.890