Protein Alignment toy and crx

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_694419.1
• Gene: crx / 81881
• ZFINID: ZDB-GENE-010403-1
• Length: 281
• Species: Danio rerio
• Alignment Length: 309
• Identity: 91/309 - (29%)
• Similarity: 126/309 - (40%)
• Gaps: 85/309 - (27%)

  Fly   263 RKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMR 327
            ||.:|.||:|:..|:|.||..|.:|.|||:|.||.:|.||.|||:|:||||.|||||.|::::
Zfish    36 RKQRRERTTFTRTQLDILEALFTKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ-- 98

  Fly   328 TQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASN 392
                         :||....|......||......|.||           |||::|:...|...
Zfish    99 -------------QTSGQPKPRPPKKKSSPPPDLTSDPG-----------TSSSVVAAPTPTVP- 138

  Fly   393 GPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQ 457
             |:|..|.|          |:...:|         |..|.:|.|:.          ||.|| |:|
Zfish   139 -PSVSAGTA----------PVSVWSP---------TSLSPLPDPLC----------GSGTP-CVQ 172

  Fly   458 QRDAYPYMFHDPLSLG--------------SPYVSAHHRNTACNPSAAHQQP---PQHGVYTNSS 505
            :...||..:..|.|..              |||:|.  ..|..:.|.....|   |..|...:.|
Zfish   173 RPAPYPMSYGQPSSYSQGYGSSPYFSGLDCSPYLSP--MTTQLSASGGALSPLTVPSMGGSLSQS 235

  Fly   506 PMPSSNTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQXSSIFGSPLDH 554
            |..||. |..:|.:.    .|:.:..|......| :|. |::  ..|||
Zfish   236 PSLSSQ-GYSTASLG----FSSVDCLDYKDQQAW-KLNFSTV--DCLDH 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	43/104 (41%)
		Homeodomain	267..322	CDD:459649	32/54 (59%)
crx	NP_694419.1	homeodomain	38..97		33/58 (57%)
		Homeodomain	49..94	CDD:459649	28/44 (64%)
		TF_Otx	152..230	CDD:427350	23/99 (23%)