Protein Alignment toy and pitx1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001035436.3
• Gene: pitx1 / 678598
• ZFINID: ZDB-GENE-060421-3623
• Length: 285
• Species: Danio rerio
• Alignment Length: 333
• Identity: 90/333 - (27%)
• Similarity: 132/333 - (39%)
• Gaps: 83/333 - (24%)

  Fly   198 LPPAASVVTSP-ANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRL 261
            ||.:||..... .|.|.::  .|.:..|.:.|||       ..:.|||::...
Zfish    11 LPRSASSTRETLENTSSES--SDTEAAEKERSVE-------QRSDDGNADDPK------------ 54

  Fly   262 KRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKM 326
            |:|.:|.||.|:::|:..||..|:|..|||:..||.:|....|.|||::|||.|||||||:.|
Zfish    55 KKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRE-- 117

  Fly   327 RTQRRS-------------ADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERT 378
            |.|:..             ....|....|.|.||          .|:...||..:::.......:
Zfish   118 RNQQMDLCKNSYLPQFSGLMQPYDDVYPTYTYNN----------WTNKGLTPAPLSTKNFTFFNS 172

  Fly   379 SSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAEN 443
            .|.|.|.|:..|.:..:.:...:...|:         |.|.:| .:|.|.:            .|
Zfish   173 MSPLTSQSMFSAPSSISSMSMASGMGHS---------AVPGMP-TTGLNNI------------GN 215

  Fly   444 YNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAA-----HQQPPQHGVYTN 503
            .| .:|..|.:........||  ..|:   |||  :.:|:| ||.|.|     .:|.|..|....
Zfish   216 LN-GIGGSTINPAMSSSTCPY--GPPV---SPY--SVYRDT-CNSSLATLRLKSKQHPSFGYSGL 271

  Fly   504 SSPMPSSN 511
            .||..|.|
Zfish   272 QSPGSSLN 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	42/127 (33%)
		Homeodomain	267..322	CDD:459649	28/54 (52%)
pitx1	NP_001035436.3	COG5576	8..>126	CDD:227863	48/137 (35%)
		Homeodomain	59..115	CDD:459649	28/55 (51%)
		OAR	247..263	CDD:461067	5/16 (31%)