DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment toy and mxtx2

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001073284.1	Gene:	mxtx2 / 58078	ZFINID:	ZDB-GENE-000710-6	Length:	296	Species:	Danio rerio

Alignment Length:	317	Identity:	82/317 - (25%)
Similarity:	123/317 - (38%)	Gaps:	70/317 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   242 DGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPE 306
            ||||:.:             |...:|.||||:.|.::.|:..|....||.:..||.|:...||||
Zfish    12 DGNSQAS-------------KIAGRRKRTSFTKEHLELLKMAFNVDPYPGISVRESLSQATGLPE 63

  Fly   307 ARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSA 371
            :||||||.|:||:..:...:    :|:..:|..   |...:|......:||..|.... ||..|.
Zfish    64 SRIQVWFQNKRARTLKNRAI----QSSPQLDNK---SPLPSPFLPPHMASVGVSAQQR-GIQESP 120

  Fly   372 INVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQP 436
            .|:....:|.......|...:.|.|...:.....|||.||....|.|.....:| :|..|  |:.
Zfish   121 FNIQMSQTSPQHFTFPPSDYSTPVVKPRQTRLMGTSSCSPSDLQATPDSWSYAG-STQIS--PES 182

  Fly   437 IATMAENYNSSLGSMTPSCLQQRDAYPY---MFHDPLSLGSPYVSAHHRNTA--------CNPSA 490
            ....|||:.:|....:|..|.....|||   ....|.|:.|...|....::|        |:||.
Zfish   183 WDVAAENFGNSYKDESPFFLYPPPPYPYGSTRVGCPSSMESLSTSPASSDSAFWDMGLENCSPSV 247

  Fly   491 AH------------QQPPQHGVYTNSSPMPSSNTGVISAGVSVPVQISTQNVSDLTG 535
            .:            :||        .:|:|               .:|:|.:.|:.|
Zfish   248 PYTSCGSPWDRLTEEQP--------VAPLP---------------DLSSQCLEDVLG 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	35/114 (31%)
		Homeobox	269..322	CDD:395001	25/52 (48%)
mxtx2	NP_001073284.1	HOX	22..76	CDD:197696	25/53 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840