Protein Alignment toy and pax7b

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_073794722.1
• Gene: pax7b / 566533
• ZFINID: ZDB-GENE-080917-54
• Length: 520
• Species: Danio rerio
• Alignment Length: 596
• Identity: 194/596 - (32%)
• Similarity: 269/596 - (45%)
• Gaps: 165/596 - (27%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
Zfish    48 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 112

  Fly    94 RAIGGSKPRVATTPVVQK-IADYKRECPSIFAWEIRDRLLSEQVCNSDNIP-----SVSSINRVL 152
            .||||||||...||.|:| |.:||||.|.:|:|||||:||.:.||:...:|     |||||:|||
Zfish   113 GAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRSTVPSGEASSVSSISRVL 177

  Fly   153 RNLASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADR 217
            |....:|:                                                       |.
Zfish   178 RARFGKKD-------------------------------------------------------DE 187

  Fly   218 DDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSG------------DEDSQMRLRLKRKLQRNRT 270
            ||..|:              |.|.:..::|:..|            |.:|:..|.||||.:|:||
Zfish   188 DDCDKK--------------DDTGEKKTKHSIDGILGDKGRMDEVSDVESEPDLPLKRKQRRSRT 238

  Fly   271 SFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADT 335
            :|:.||::.|||.||||||||::.||.||.:..|.|||:|||||||||:||::
Zfish   239 TFTAEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ------------ 291

  Fly   336 VDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGE 400
                            ..::.:|..|:..||      .........|.:..|||:|...|.|..:
Zfish   292 ----------------AGANQLAAFNHLLPG------GFPPTGMPTLPTYQLPESSYPTTTLPQD 334

  Fly   401 -ANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPY 464
             :.|.|..      ||..|......|.::..||     |....:...|..|.|.:.:.|..:..:
Zfish   335 VSGTVHRP------QPLPPSTMHQGGLSSDSSS-----AYGLSSNRHSFSSYTDTFMSQSASSNH 388

  Fly   465 MFHDPLSLG-SPYVSAHHRNTACNPSAAHQQP-------PQHGVYTNSSPMPSS---NTGVISAG 518
            |  :|:|.| ||.|    .:...||||...||       |.|.....|:|:.:|   .:..|...
Zfish   389 M--NPVSNGLSPQV----MSILSNPSAVAPQPQHEFSISPLHSSLEASNPISASCSQRSEPIKTA 447

  Fly   519 VSVPVQ-------ISTQNVS-DLTGSNYWPRLQXSSIFGSPLDHLSKATAAAIIAAQAAEKSHKH 575
            .|:|..       .||.:.| |...:.|    |.|....:.:|:|:|..:   ::.|...|..:|
Zfish   448 DSLPSSQSYCPPTYSTTSYSVDPVTAGY----QYSQYGQTAVDYLAKNVS---LSTQRRMKLGEH 505

  Fly   576 RKEHSIVSIHT 586
            .....::.:.|
Zfish   506 SAVLGLLQVET 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	81/129 (63%)
		COG5576	<253..368	CDD:227863	46/114 (40%)
		Homeodomain	267..322	CDD:459649	35/54 (65%)
pax7b	XP_073794722.1	None