DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and Pdlim3

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001361581.1	Gene:	Pdlim3 / 53318	MGIID:	1859274	Length:	364	Species:	Mus musculus

Alignment Length:	202	Identity:	51/202 - (25%)
Similarity:	73/202 - (36%)	Gaps:	47/202 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 GRTSTANNPSGT------TASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLG 398
            ||||..:.|||.      :..|||:|.:...||.:..|..:|....   :...||    |..::.
Mouse   130 GRTSGCSTPSGVDCGSGRSTPSSVSTVSTICPGDLKVAAKMAPNIP---LEMELP----GVKIVH 187

  Fly   399 GEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYP 463
            .:.||        |:|       |.|..|.|.:...|....:.|  .||:...|.|...|.|.|
Mouse   188 AQFNT--------PMQ-------LYSDDNIMETLQGQVATALGE--TSSMSEPTASVPPQSDVY- 234

  Fly   464 YMFHD-------PLSLGSPYVSAHHRNTACNPSAAHQQPPQ------HGVYTNSSPMP---SSNT 512
            .|.||       |...||..|.....|...:...|..:..:      ||...::..||   ...:
Mouse   235 RMLHDNRDDPAAPRQSGSFRVLQDLVNDGPDDRPAGTRSVRAPVTKVHGGAGSAQRMPLCDKCGS 299

  Fly   513 GVISAGV 519
            |::.|.|
Mouse   300 GIVGAVV 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	13/33 (39%)
		Homeobox	269..322	CDD:395001
Pdlim3	NP_001361581.1	PDZ_signaling	2..80	CDD:238492
		DUF4749	184..268	CDD:374237	25/101 (25%)
		LIM_ALP	294..346	CDD:188834	3/13 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030