Protein Alignment toy and PAX7

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_002575.1
• Gene: PAX7 / 5081
• HGNCID: 8621
• Length: 520
• Species: Homo sapiens
• Alignment Length: 518
• Identity: 183/518 - (35%)
• Similarity: 240/518 - (46%)
• Gaps: 138/518 - (26%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
Human    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    94 RAIGGSKPR-VATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPS--VSSINRVLRNL 155
            .|||||||| |||..|.:||.:||||.|.:|:||||||||.:..|:...:||  ||||:||||..
Human    99 GAIGGSKPRQVATPDVEKKIEEYKRENPGMFSWEIRDRLLKDGHCDRSTVPSGLVSSISRVLRIK 163

  Fly   156 ASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDV 220
            ..:||::                                                       |:.
Human   164 FGKKEEE-------------------------------------------------------DEA 173

  Fly   221 QKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFE 285
            .|:|.....:..|:........||.....| |.:|:..|.||||.:|:||:|:.||::.|||.||
Human   174 DKKEDDGEKKAKHSIDGILGDKGNRLDEGS-DVESEPDLPLKRKQRRSRTTFTAEQLEELEKAFE 237

  Fly   286 RTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSG 350
            ||||||::.||.||.:..|.|||:|||||||||:||::
Human   238 RTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ--------------------------- 275

  Fly   351 TTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVL---GGEANTTHTSSESPP 412
             ..::.:|..|:..||      .........|....||:::...|.:   ||  :|.|.....||
Human   276 -AGANQLAAFNHLLPG------GFPPTGMPTLPPYQLPDSTYPTTTISQDGG--STVHRPQPLPP 331

  Fly   413 -------LQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPL 470
                   |..||.....:|.:...:|         ..:|:.|.  |.|       |.|....:|:
Human   332 STMHQGGLAAAAAAADTSSAYGARHS---------FSSYSDSF--MNP-------AAPSNHMNPV 378

  Fly   471 SLG-SPYVSAHHRNTACNPSAAHQQP-------PQHG---VYTNSSPMPSSNTGVISAGVSVP 522
            |.| ||.|    .:...||||...||       |.||   ..|:.|...|.....|..|.|:|
Human   379 SNGLSPQV----MSILGNPSAVPPQPQADFSISPLHGGLDSATSISASCSQRADSIKPGDSLP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	82/126 (65%)
		COG5576	<253..368	CDD:227863	46/114 (40%)
		Homeobox	269..322	CDD:395001	34/52 (65%)
PAX7	NP_002575.1	paired box domain	34..164		84/129 (65%)
		PAX	34..163	CDD:238076	84/128 (66%)
		octapeptide	86..93		4/6 (67%)
		paired homeodomain	217..275		36/57 (63%)
		Homeobox	220..273	CDD:278475	33/52 (63%)
		Pax7	347..385	CDD:289156	12/55 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..409		6/19 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810