Protein Alignment toy and PAX4

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001353039.1
• Gene: PAX4 / 5078
• HGNCID: 8618
• Length: 351
• Species: Homo sapiens
• Alignment Length: 443
• Identity: 162/443 - (36%)
• Similarity: 218/443 - (49%)
• Gaps: 119/443 - (26%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |.|.:|||||::|||||||..|||:||.||.||.|||||||||:||||||||||||||.||.::|
Human     5 GISSMNQLGGLFVNGRPLPLDTRQQIVRLAVSGMRPCDISRILKVSNGCVSKILGRYYRTGVLEP 69

  Fly    94 RAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLASQ 158
            :.|||||||:||.|||.:||..|.|||::|||||:.:|.:|.:|..|..|||||||||||
Human    70 KGIGGSKPRLATPPVVARIAQLKGECPALFAWEIQRQLCAEGLCTQDKTPSVSSINRVLR----- 129

  Fly   159 KEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQKR 223
                |.|:::.:                 |.....:...|.||   |.:|
Human   130 ----ALQEDQGL-----------------PCTRLRSPAVLAPA---VLTP--------------- 155

  Fly   224 ELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTH 288
                         |..:......|..:|              .||||.||..|.::|||||:|..
Human   156 -------------HSGSETPRGTHPGTG--------------HRNRTIFSPSQAEALEKEFQRGQ 193

  Fly   289 YPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTA 353
            |||..||.:||....|||..::||||||||||||:||::.:.:                   ...
Human   194 YPDSVARGKLATATSLPEDTVRVWFSNRRAKWRRQEKLKWEMQ-------------------LPG 239

  Fly   354 SSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASN-GPTV--LGGEANTTHTSSESPP--- 412
            :|...|.....|||::     |:::..::.:.:||.... ||:.  |..........|::||
Human   240 ASQGLTVPRVAPGIIS-----AQQSPGSVPTAALPALEPLGPSCYQLCWATAPERCLSDTPPKAC 299

  Fly   413 LQPAAPRLP-----LNSGFNTMYSSIPQP-----IATMAENYNSSLGSMTPSC 455
            |:|....||     |:||.    ..:|.|     :|::    :.|...:.|.|
Human   300 LKPCWGHLPPQPNSLDSGL----LCLPCPSSHCHLASL----SGSQALLWPGC 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	85/123 (69%)
		COG5576	<253..368	CDD:227863	41/114 (36%)
		Homeobox	269..322	CDD:395001	31/52 (60%)
PAX4	NP_001353039.1	PAX	5..129	CDD:128645	85/123 (69%)
		Homeobox	174..226	CDD:306543	30/51 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1152885at2759
OrthoFinder	1	1.000	-	-		FOG0002521
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45636
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020