Protein Alignment toy and Pax5

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_038966491.1
• Gene: Pax5 / 500453
• RGDID: 1565236
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 172/498 - (34%)
• Similarity: 226/498 - (45%)
• Gaps: 144/498 - (28%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            ||.|:||||||:||||||||..||:||||||.|.|||||||.|:||:||||||||||||||||||
  Rat    16 GHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIKP 80

  Fly    94 RAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLASQ 158
            ..||||||:|||..||:|||:|||:.|::||||||||||:|:||::|.:||||||||::|....|
  Rat    81 GVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSINRIIRTKVQQ 145

  Fly   159 -KEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASV--------VTSPANLSGQ 214
             ..|.....:.|:.        .||      |.|..:.::...|.|.        :|||:
  Rat   146 PPNQPVPASSHSIV--------STG------SVTQVSSVSTDSAGSSYSISGILGITSPS----- 191

  Fly   215 ADRDDVQKRELQFSVEVSHT-NSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQID 278
               .|..||:....::.|.. |.|.............||                  .|:.:|::
  Rat   192 ---ADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGD------------------LFTQQQLE 235

  Fly   279 SLEKEFERTHYPDVFA---------------RERLADKIGLPEARIQVWFSNRRAKWRREEKMRT 328
            .|::.|||.||.|:|.               |:.||.    |:|   |.|..            |
  Rat   236 VLDRVFERQHYSDIFTTTEPIKPEQWCPVLMRQYLAQ----PQA---VLFQT------------T 281

  Fly   329 QRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNG 393
            :..:..::.||.....||..|.|.|.                            :.:|:|...:.
  Rat   282 EYSAMASLAGSLDDMKANLTSPTPAD----------------------------IGSSVPGPQSY 318

  Fly   394 PTVLGGEANTTHTSSESPPLQPA------APRL----PLNSGFNTMYSSIPQPIATMAENYNSSL 448
            |.|.|.:..:|......|.:.||      ||.|    | .|.|:....|.||     ..:||.|
  Rat   319 PIVTGRDLASTTLPGYPPHVPPAGQGSYSAPTLTGMVP-GSEFSGSPYSHPQ-----YSSYNDS- 376

  Fly   449 GSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAA 491
                           :.|.:|..|||||..:.....|..|:||
  Rat   377 ---------------WRFPNPGLLGSPYYYSAAARGAAPPAAA 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	94/123 (76%)
		COG5576	<253..368	CDD:227863	25/129 (19%)
		Homeodomain	267..322	CDD:459649	17/69 (25%)
Pax5	XP_038966491.1	PAX	16..140	CDD:128645	94/123 (76%)
		Pax2_C	298..409	CDD:463563	37/157 (24%)