Protein Alignment toy and sv

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_524633.3
• Gene: sv / 43825
• FlyBaseID: FBgn0005561
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 207/712 - (29%)
• Similarity: 306/712 - (42%)
• Gaps: 200/712 - (28%)

  Fly    14 HSSVGQSTLFGCSTAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCV 78
            |||.|     ..|..||.|:||||||:||||||||..||:||||||:|.|||||||.|:||:|||
  Fly   165 HSSQG-----SISGDGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHNGVRPCDISRQLRVSHGCV 224

  Fly    79 SKILGRYYETGSIKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIP 143
            ||||.|||||||.|...||||||:|||.|||..||:||||.|::||||||||||:|.:|:.||:|
  Fly   225 SKILSRYYETGSFKAGVIGGSKPKVATPPVVDAIANYKRENPTMFAWEIRDRLLAEAICSQDNVP 289

  Fly   144 SVSSINRVLRNLASQKEQQA-QQQNESVYEKL-------RMFNGQTG--GWAWYPSNTTTA---- 194
            |||||||::||.|::|.:.. ..|...|.:.|       ...:..||  |....|::.::|
  Fly   290 SVSSINRIVRNKAAEKAKHVHHHQQHHVSQSLGGGHIATESVDSSTGTIGEPQPPTSNSSANSVN 354

  Fly   195 ---------HLTLPPAA--SVVTSPANLSGQAD-----RDDVQKRELQFSVE----VSHTNSHDS 239
                     |.::|.:.  ||..|..:::..::     ....::|...:|:.    :.|.:...:
  Fly   355 TNVSASASVHASIPTSGTDSVQVSVGHINANSNETTHINSTAEQRTTGYSINGILGIQHGHHSHN 419

  Fly   240 TSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGL 304
            .::.:|.:|::..|.|..|.|::...:.:.|:..::..|.              .|:|::...|
  Fly   420 NNNNSSVNNNNNTESSCKRKRIEAHDENHDTNIHSDNDDG--------------KRQRMSTYSG- 469

  Fly   305 PEARIQVWFSNRRAKW--RREEKMRTQ--RRSADT------------------VDGSGRTSTANN 347
            .:....:|    ..||  :.:.|:..:  ..:|.|                  :.|||.|::.|:
  Fly   470 DQLYTNIW----SGKWCIKDDHKLLAELGNLTASTGNCPATYYEASNGFSTTPISGSGATASGND 530

  Fly   348 PSGTTASSSVATSNNSTPGIVNSAINVAERTSS------------ALVSNSLPEASNGP--TVLG 398
            .|  ....|:.|.:.:...|...||..:..|.|            .|.:||:.|.:..|  |.|.
  Fly   531 TS--MLYDSITTISQTQSSIYTPAIGPSIGTGSLTPLVPISMHEMKLSANSIQEQTVPPFYTALA 593

  Fly   399 GEANTTH-------------------TSSESPPLQPAAPRL--------------PLNSGFNTMY 430
            .:.|.|.                   .||:|..|.|.:.|:              ||.:......
  Fly   594 FDGNYTSMTSLENCSSLVGQEHIVMPESSDSNTLCPISTRIVPDITETNSTRVKEPLTNSDGCSE 658

  Fly   431 SSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHR---NTACNPSAAH 492
            .:..:|     |..|||..|       ...|.|::.|    :|...:..:.|   |.:.:||:..
  Fly   659 DNNKEP-----EKSNSSQSS-------DHIASPHLHH----IGEEQLRGNRRSNLNASTHPSSLI 707

  Fly   493 QQPPQH------------------------GVYTNSSPMPSSNTGVISAGVSVPVQIS------- 526
            ...|..                        |:|:..:.:||.|.  .|||.|..|..|
  Fly   708 PLQPSGGSSLLNINPSENRSDVELNLSNNVGLYSTPTVLPSFNH--YSAGCSSVVPGSDYAYNPA 770

  Fly   527 -TQ-----------NVSDLTGSNYWPRLQXSSIFGSPLDHLSK----ATAAAIIAAQAAEKS 572
             ||           ..|.|..|:|:   ..|....|||.|..:    ||.|..:|:.|:..|
  Fly   771 YTQYGGAYGSYGYGTGSGLINSSYY---YESGQTQSPLTHDLRSPLVATRANSLASAASPGS 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	92/123 (75%)
		COG5576	<253..368	CDD:227863	23/136 (17%)
		Homeodomain	267..322	CDD:459649	8/56 (14%)
sv	NP_524633.3	PAX	175..299	CDD:128645	92/123 (75%)