Protein Alignment toy and Rx

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_726006.3
• Gene: Rx / 37367
• FlyBaseID: FBgn0020617
• Length: 904
• Species: Drosophila melanogaster
• Alignment Length: 717
• Identity: 166/717 - (23%)
• Similarity: 249/717 - (34%)
• Gaps: 202/717 - (28%)

  Fly     7 HIMHGHP----HSSVGQSTLFGCSTAGH--SGINQLGGVYVNG---------------------R 44
            |..||||    |:..|....||....||  ....:..|.|:|.                     .
  Fly   255 HAGHGHPTHHGHAPFGYHNAFGFGQGGHGYGHPEEAAGNYLNSMHQMVEANQLQTGANGANPPPA 319

  Fly    45 PLPDST----RQKIVELA---------HS--------GARPCDISRILQVSNGCVSKILGRYY-- 86
            |||.|:    :|.:..||         ||        ||.|              ....|.|:
  Fly   320 PLPPSSFGSHQQHLAALAAQAQEQQNQHSKYAKSSPTGAGP--------------PPPPGAYFME 370

  Fly    87 -ETGSIKPRAIGGSKPRVAT----------------------TPVVQKIADYKRECPSIFAWEIR 128
             :|..:.|..|...:..:::                      ||..:.....||:...:|..:..
  Fly   371 SQTAPVAPSQINYDERSMSSASDLEEDDDDAAKLQLDVTSPPTPSPRGQLAAKRKSAGVFCDDNE 435

  Fly   129 DRLLSEQVCNSD---NIPSVSSINRVLRNLASQKEQQAQQQNESVYEK-------LRMFNGQTGG 183
            .:|.:.|:...:   ...|:..::...::...|::||.|||.:.:.::       ....||...|
  Fly   436 PKLANGQLPGGNYGIRPRSMEEVHHQQQSHHHQQQQQQQQQQQQLQQQQGFQHDFRNSGNGNPNG 500

  Fly   184 WAWYPSNTTTAHLTLPPAASVVTSPANLSGQ---ADRDDVQKRELQFSVEVSHTNSHDSTSDGNS 245
                                  .|.:...|:   ||.|.:.......|.:::.|||    |:...
  Fly   501 ----------------------NSNSGDHGERLNADSDSLVNGSCASSEDLNQTNS----SEQGE 539

  Fly   246 EHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQ 310
            :..|..|::.|.....|:|.:||||:|:..|:..||:.||::|||||::||.||.|:.|||.|:|
  Fly   540 KITSGSDDEGQDDNCAKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAMKVNLPEVRVQ 604

  Fly   311 VWFSNRRAKWRREEKMRTQRRSADTVD------GSGRTSTANNP----------SGTTASSSVAT 359
            |||.||||||||:||..:.|.......      |.|.:....:|          .|..:......
  Fly   605 VWFQNRRAKWRRQEKSESLRLGLTHFTQLPHRLGCGASGLPVDPWLSPPLLSALPGFLSHPQTVY 669

  Fly   360 SNNSTPGIVNSAINVAERTSSALVSNSLPEASNGP----TVLGGEANTTHTSSESPPLQPAAPRL 420
            .:..||.:..:..|:   |.|:|.:.....|.|||    ...||     |...:.||  |..|.
  Fly   670 PSYLTPPLSLAPGNL---TMSSLAAMGHHHAHNGPPPPHVGHGG-----HGQPQPPP--PPPPH- 723

  Fly   421 PLNSGFNTMYSSIPQPIAT----MAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHH 481
                       .:|.|..:    ...:.:..|..|:|..              .|||||    ||
  Fly   724 -----------GVPHPHGSHHVVPLSHLSPHLSRMSPHA--------------TSLGSP----HH 759

  Fly   482 RNTACNPSAAHQQPPQHGVYT---NSSPMPSSNTGVISAGVSV---PVQISTQNV-SDLTGSNYW 539
            ..|..........||.....|   :||...||:..:..:|..|   |..:|..|. |:..|.:..
  Fly   760 GVTPLGTPLHSSLPPSSTATTVAVSSSQSSSSSASLECSGPDVCMSPQNLSIGNADSNGDGRDLS 824

  Fly   540 PRLQXSSIFGSPLDHLSKATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTTCCS 604
            ..|. .|...:|...|.|..|:|.|     |.....|.........|.|....||:..|..:..:
  Fly   825 SDLDAGSTSSNPGSSLDKCAASANI-----ELLDVGRDSPPPPPTPTGKGSSTPPTDMRSNSIAT 884

  Fly   605 SR 606
            .|
  Fly   885 LR 886

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	30/195 (15%)
		COG5576	<253..368	CDD:227863	48/130 (37%)
		Homeodomain	267..322	CDD:459649	34/54 (63%)
Rx	NP_726006.3	Homeodomain	560..616	CDD:459649	34/55 (62%)
		OAR	876..892	CDD:461067	2/11 (18%)