Protein Alignment toy and Alx3

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_001007013.2
• Gene: Alx3 / 365900
• RGDID: 1359270
• Length: 343
• Species: Rattus norvegicus
• Alignment Length: 359
• Identity: 94/359 - (26%)
• Similarity: 124/359 - (34%)
• Gaps: 158/359 - (44%)

  Fly   249 SSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWF 313
            |.|..||....:.|.|.:||||:||..|::.|||.|::||||||:|||:||.:..|.|||:||||
  Rat   137 SPGLPDSMELAKSKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWF 201

  Fly   314 SNRRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAERT 378
            .|||||||:.|:.             |:.....||..|....||....:|.|.:.||
  Rat   202 QNRRAKWRKRERY-------------GKIQEGRNPFTTAYDISVLPRTDSHPQLQNS-------- 245

  Fly   379 SSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAEN 443
               |.|:....:..||.::             ||                  ..||.|
  Rat   246 ---LWSSPGSGSPGGPCLM-------------PP------------------EGIPSP------- 269

  Fly   444 YNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTA------CNPSAAHQQPPQHGVYT 502
                       |:                 ||| |..|.|.|      .:| |||.     |:|:
  Rat   270 -----------CM-----------------SPY-SHSHGNVAGFMGVPASP-AAHP-----GIYS 299

  Fly   503 NSSPMPSSNTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQXSSIFGSPLDHLSKATAAAIIAAQ 567
            .....|:                       |.|.::.|         ||
  Rat   300 IHGFPPA-----------------------LGGHSFEP---------SP---------------- 316

  Fly   568 AAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTT 601
                 ....|..|:||:.  .:.|.||||...||
  Rat   317 -----DGDYKSPSLVSLR--MKPKEPPSLLNWTT 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	50/114 (44%)
		Homeodomain	267..322	CDD:459649	36/54 (67%)
Alx3	NP_001007013.2	Homeodomain	154..210	CDD:459649	36/55 (65%)