DRSC/TRiP Functional Genomics Resources

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Protein Alignment toy and Pax9

DIOPT Version :9

Sequence 1:NP_001368990.1 Gene:toy / 43833 FlyBaseID:FBgn0019650 Length:655 Species:Drosophila melanogaster
Sequence 2:NP_001034628.1 Gene:Pax9 / 362741 RGDID:1560838 Length:342 Species:Rattus norvegicus


Alignment Length:272 Identity:115/272 - (42%)
Similarity:146/272 - (53%) Gaps:54/272 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 INQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKPRAIG 97
            :||||||:|||||||::.|.:|||||..|.|||||||.|:||:|||||||.||.|||||.|.|||
  Rat     8 VNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIG 72

  Fly    98 GSKPRVATTPVVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLR----NLASQ 158
            ||||||.|..||:.|..||:..|.|||||||||||::.||:..|:||||||:|:||    |||.|
  Rat    73 GSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQ 137

  Fly   159 KEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDDVQKR 223
            ....:.:|::...:....:|....    |||..|.|...:|....|...|.              
  Rat   138 GHYDSYKQHQPAPQPALPYNHIYS----YPSPITAAAAKVPTPPGVPAIPG-------------- 184

  Fly   224 ELQFSVEVSHT--NSHDST-------------SDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFS 273
                ||.:..|  :||..|             ||.:..|:...:|.|.:          .|.:||
  Rat   185 ----SVALPRTWPSSHSVTDILGIRSITDQGVSDSSPYHSPKVEEWSSL----------GRNNFS 235

  Fly   274 ---NEQIDSLEK 282
               ...::.|||
  Rat   236 AAAPHAVNGLEK 247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
toyNP_001368990.1 PAX 29..153 CDD:128645 82/119 (69%)
COG5576 <253..368 CDD:227863 8/33 (24%)
Homeobox 269..322 CDD:395001 6/17 (35%)
Pax9NP_001034628.1 PAX 6..131 CDD:238076 84/122 (69%)
PAI subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 7..63 39/54 (72%)
RED subdomain. /evidence=ECO:0000255|PROSITE-ProRule:PRU00381 82..130 29/47 (62%)
Interaction with KDM5B. /evidence=ECO:0000250 168..189 6/38 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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