DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and Gsc

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_001137762.2	Gene:	Gsc / 33240	FlyBaseID:	FBgn0010323	Length:	473	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	72/204 - (35%)
Similarity:	98/204 - (48%)	Gaps:	35/204 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   183 GWAWYPSNTTTAHLTLPP----AASV-----VTSPANLSGQADRDDVQKRELQFSVEVSHTNSHD 238
            |:|..||:...|:....|    ||:|     ....|::||.|             ..:|....|.
  Fly   255 GFAASPSDFLVAYPNFYPNYMHAAAVAHVAAAQMQAHVSGAA-------------AGLSGHGHHP 306

  Fly   239 STSDGNSEHNSSG-DEDSQMRLR-------LKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFAR 295
            ....|:..|...| ....|..|.       .||| :|:||.|:.||::.||..|::||||||..|
  Fly   307 HHPHGHPHHPHLGAHHHGQHHLSHLGHGPPPKRK-RRHRTIFTEEQLEQLEATFDKTHYPDVVLR 370

  Fly   296 ERLADKIGLPEARIQVWFSNRRAKWR---REEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSV 357
            |:||.|:.|.|.|::|||.|||||||   |||:.|. |:..:...||....|.|:.||||:|:..
  Fly   371 EQLALKVDLKEERVEVWFKNRRAKWRKQKREEQERL-RKLQEEQCGSTTNGTTNSSSGTTSSTGN 434

  Fly   358 ATSNNSTPG 366
            .:.....||
  Fly   435 GSLTVKCPG 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	54/124 (44%)
		Homeobox	269..322	CDD:395001	32/55 (58%)
Gsc	NP_001137762.2	Homeobox	343..396	CDD:278475	30/52 (58%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6207
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940