DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment toy and sdcbp2

DIOPT Version :9

Sequence 1:	NP_001368990.1	Gene:	toy / 43833	FlyBaseID:	FBgn0019650	Length:	655	Species:	Drosophila melanogaster
Sequence 2:	NP_997856.1	Gene:	sdcbp2 / 325004	ZFINID:	ZDB-GENE-030131-3727	Length:	299	Species:	Danio rerio

Alignment Length:	306	Identity:	60/306 - (19%)
Similarity:	99/306 - (32%)	Gaps:	112/306 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   396 VLGGEANTTHTSSESPPL-------QPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTP 453
            |:..::...:.:|.:|.:       |||...:|    .:|:|.::.:            ||.
Zfish    15 VIRAQSQFANATSSTPAITQGAYQPQPATQGMP----SSTLYPNLEE------------LGD--- 60

  Fly   454 SCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMPSSNTGV---- 514
                      ||   .|||.|..|   .||.|..|.|.....|. .|.....|:..::.|:
Zfish    61 ----------YM---GLSLNSDEV---QRNLALVPVATQVAVPS-SVGGMVRPVTGADMGIRRAE 108

  Fly   515 ------------------------ISAGVSVPVQISTQNVSDLTGSNYWP---RLQXSSIFGSPL 552
                                    |..||.|.: :...:.:.|.|..:..   ::...::.|...
Zfish   109 IRPGLREVILCKDQEGKVGLRLRDIDNGVFVQL-VQANSPAALAGLRFGDQVLQINGQNVAGWNS 172

  Fly   553 DHLSKATAAAIIAAQAAEKSHKHRKEHSIVSIHTTKRKKNPPSLKRQTTCCSSRYLNMTFGAGKD 617
            |...||..||  |.|..|...:.|.....:::|..                ||.::...|.:|:.
Zfish   173 DKAHKALKAA--AEQRIELIVRDRPFQRTITMHKD----------------SSGHVGFIFKSGRI 219

  Fly   618 VDVV-----IGQGLIVSLTPH----ISGKPELFGSPNVNYHQDFQV 654
            ..:|     ...||   ||.|    |:|:       ||...:|.|:
Zfish   220 TSLVKDGSAARNGL---LTEHYICEINGQ-------NVIGLKDTQI 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863
		Homeobox	269..322	CDD:395001
sdcbp2	NP_997856.1	PDZ_signaling	113..>173	CDD:238492	7/60 (12%)
sdcbp2	NP_997856.1	PDZ_signaling	198..270	CDD:238492	17/84 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900