Protein Alignment toy and pax7a

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571400.1
• Gene: pax7a / 30587
• ZFINID: ZDB-GENE-990415-201
• Length: 507
• Species: Danio rerio
• Alignment Length: 585
• Identity: 190/585 - (32%)
• Similarity: 265/585 - (45%)
• Gaps: 142/585 - (24%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
Zfish    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    94 RAIGGSKPRVATTPVVQK-IADYKRECPSIFAWEIRDRLLSEQVCNSDNIP-----SVSSINRVL 152
            .||||||||...||.|:| |.:||||.|.:|:|||||:||.:.||:...:|     |||||:|||
Zfish    99 GAIGGSKPRQVATPDVEKRIEEYKRENPGMFSWEIRDKLLKDGVCDRGTVPSGEASSVSSISRVL 163

  Fly   153 RNLASQKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADR 217
            |....:|:                                                       |.
Zfish   164 RARFGKKD-------------------------------------------------------DD 173

  Fly   218 DDVQKRELQFSVEVSHTNSHDSTSDGNSEHNSSGDEDSQMRLRLKRKLQRNRTSFSNEQIDSLEK 282
            |:..|::.....:..|:........||.....| |.:|:..|.||||.:|:||:|:.||::.|||
Zfish   174 DECDKKDEDGEKKTKHSIDGILGDKGNRTDEGS-DVESEPDLPLKRKQRRSRTTFTAEQLEELEK 237

  Fly   283 EFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANN 347
            .||||||||::.||.||.:..|.|||:|||||||||:||::
Zfish   238 AFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQ------------------------ 278

  Fly   348 PSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTT-HTSSESP 411
                ..::.:|..|:..||      .........|.:..|||::...|.|..:.::| |.....|
Zfish   279 ----AGANQLAAFNHLLPG------GFPPTGMPTLPTYQLPESTYPSTTLSQDGSSTLHRPQPLP 333

  Fly   412 PLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLG-SP 475
            |.......|..:||.....||.....::.:|.:      |:|:.....       .:|:|.| ||
Zfish   334 PSSMHQGGLSADSGSAYGLSSNRHTFSSYSETF------MSPTASSNH-------MNPVSNGLSP 385

  Fly   476 YVSAHHRNTACNPSAAHQQP-------PQHGVYTNSSPMPSSNTGVISAGVSVPVQISTQ----- 528
            .|    .:...||||...||       |.||....|:|:.:|.:.......||....|||
Zfish   386 QV----MSILSNPSAVPSQPQHDFSISPLHGGLEASNPISASCSQRSDPIKSVDSLASTQSYCPP 446

  Fly   529 -------NVSDLTGSNYWPRLQXSSIFGSPLDHLSKATAAAIIAAQAAEKSHKHRKEHSIVSIHT 586
                   :|..:|..     .| |....:.:|:|:|..:   ::.|...|...|.....::.:.|
Zfish   447 TYSATSYSVDPVTAG-----YQYSQYGQTAVDYLAKNVS---LSTQRRMKLGDHSAVLGLLQVET 503

  Fly   587  586
            Zfish   504  503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	81/129 (63%)
		COG5576	<253..368	CDD:227863	46/114 (40%)
		Homeodomain	267..322	CDD:459649	35/54 (65%)
pax7a	NP_571400.1	PAX	34..166	CDD:238076	83/131 (63%)
		Homeodomain	221..277	CDD:459649	35/55 (64%)
		Pax7	343..386	CDD:403540	11/55 (20%)