Protein Alignment toy and pax6a

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: XP_009296153.1
• Gene: pax6a / 30567
• ZFINID: ZDB-GENE-990415-200
• Length: 459
• Species: Danio rerio
• Alignment Length: 562
• Identity: 276/562 - (49%)
• Similarity: 319/562 - (56%)
• Gaps: 152/562 - (27%)

  Fly    15 SSVGQSTLFGCSTAGHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQ------- 72
            :|:.|:.::.....||||:||||||:||||||||||||||||||||||||||||||||
Zfish    17 ASMMQNKVYDICNEGHSGVNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKV 81

  Fly    73 -------VSNGCVSKILGRYYETGSIKPRAIGGSKPRVATTPVVQKIADYKRECPSIFAWEIRDR 130
                   |||||||||||||||||||:|||||||||||||..||.|||.||||||||||||||||
Zfish    82 QVLDNENVSNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVGKIAQYKRECPSIFAWEIRDR 146

  Fly   131 LLSEQVCNSDNIPSVSSINRVLRNLASQKEQQAQQQNESVYEKLRMFNGQTGGW----AWYPSNT 191
            ||||.||.:||||||||||||||||||:|:|...   :.:||||||.|||||.|    .|||.
Zfish   147 LLSEGVCTNDNIPSVSSINRVLRNLASEKQQMGA---DGMYEKLRMLNGQTGTWGTRPGWYPG-- 206

  Fly   192 TTAHLTLPPAASVVTSPANLSGQADRDDVQKRELQFSVEVSHTNSHDSTSDGNSEHN---SSGDE 253
                             .::.||.::|..|:                  |||..|:.   ||..|
Zfish   207 -----------------TSVPGQPNQDGCQQ------------------SDGGGENTNSISSNGE 236

  Fly   254 DS---QMRLRLKRKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSN 315
            ||   ||||:||||||||||||:.|||::||||||||||||||||||||.||.||||||||||||
Zfish   237 DSDETQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARERLAAKIDLPEARIQVWFSN 301

  Fly   316 RRAKWRREEKMRTQRRSADTVDGSGRTSTANNPSGTTASSSVATS------NNSTPGIVNSAINV 374
            ||||||||||:|.|||.|           :|:.|....|||.:||      ..:||
Zfish   302 RRAKWRREEKLRNQRRQA-----------SNSSSHIPISSSFSTSVYQPIPQPTTP--------- 346

  Fly   375 AERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIAT 439
            ...||.:::..|             :...|:|.|..||:                      |..|
Zfish   347 VSFTSGSMLGRS-------------DTALTNTYSALPPM----------------------PSFT 376

  Fly   440 MAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVSAHHRNTACNPSAAHQQPPQHGVYTNS 504
            ||.|.     .|.||   |..:|..|...     ||.|:....:|        ..||....:.||
Zfish   377 MANNL-----PMQPS---QTSSYSCMLPT-----SPSVNGRSYDT--------YTPPHMQAHMNS 420

  Fly   505 SPMPSS---NTGVISAGVSVPVQISTQNVSDLTGSNYWPRLQ 543
            ..|.:|   :||:||.|||||||:..   |:...|.||||||
Zfish   421 QSMAASGTTSTGLISPGVSVPVQVPG---SEPDMSQYWPRLQ 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	113/137 (82%)
		COG5576	<253..368	CDD:227863	80/123 (65%)
		Homeodomain	267..322	CDD:459649	48/54 (89%)
pax6a	XP_009296153.1	PAX	31..169	CDD:128645	113/137 (82%)
		Homeodomain	253..308	CDD:459649	48/54 (89%)