Protein Alignment toy and pax3a

DIOPT Version :9

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 560
• Identity: 193/560 - (34%)
• Similarity: 264/560 - (47%)
• Gaps: 154/560 - (27%)

  Fly    29 GHSGINQLGGVYVNGRPLPDSTRQKIVELAHSGARPCDISRILQVSNGCVSKILGRYYETGSIKP 93
            |...:||||||::||||||:..|.||||:||.|.|||.|||.|:||:|||||||.||.|||||:|
Zfish    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    94 RAIGGSKPRVATTP-VVQKIADYKRECPSIFAWEIRDRLLSEQVCNSDNIPSVSSINRVLRNLAS 157
            .|||||||:.:||| |.:||.:||||.|.:|:|||||:||.:.:|:.:|:||||||:|:||
Zfish    99 GAIGGSKPKQSTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDGICDRNNVPSVSSISRMLR---- 159

  Fly   158 QKEQQAQQQNESVYEKLRMFNGQTGGWAWYPSNTTTAHLTLPPAASVVTSPANLSGQADRDD--V 220
                                 .:.||                            :|..|.||  |
Zfish   160 ---------------------CKFGG----------------------------NGDEDEDDDEV 175

  Fly   221 QKRELQFSVEVSHTNSHDSTSDGNSEHNSSG-DEDSQMRLRLKRKLQRNRTSFSNEQIDSLEKEF 284
            :|||::.: |....:|.|......|.|:..| |.||:..|.||||.:|:||:|:.||::.||:.|
Zfish   176 EKREIEEN-ERRAKHSIDGILGDRSSHSDEGSDVDSEPGLPLKRKQRRSRTTFTAEQLEELERAF 239

  Fly   285 ERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMRTQRRSADTVDGSGRTSTANN-- 347
            |||||||::.||.||.:..|.|||:|||||||||:||::.             |:.:....|:
Zfish   240 ERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQA-------------GANQLMAFNHLI 291

  Fly   348 PSGTTASSSVATSNNSTPGIVNSAINVAERTSSALVSNSLPEASNGPTVLGGEANTTHTSSESPP 412
            |.|...|:.             |::...:...|....:|:.:.|..|       :|.|.....||
Zfish   292 PGGFPPSAM-------------SSLQPYQLADSPYPPSSISQVSEQP-------STVHRPQPLPP 336

  Fly   413 LQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNSSLGSMTPSCLQQRDAYPYMFHDPLSLG---- 473
                              :|:.|          |.||| .|...:...||      .||.|
Zfish   337 ------------------TSVHQ----------SGLGS-GPGAQEGSSAY------CLSSGRHGF 366

  Fly   474 ----SPYVSAHHRNTACNPSAAHQQPPQHGVYTNSSPMP---------SSNTGVISAGVSVPVQI 525
                ..||:|.......|||.::..|.|.....|...:|         |..||.:.....:|...
Zfish   367 SGYSDGYVAAPGHANPVNPSISNGLPSQVMGLLNPGAVPHQPQSDFALSPLTGGLEPSTGMPASC 431

  Fly   526 -STQNVSDLTGSNYWPRLQXS-----SIFGSP---LDHLS 556
             |:|.:..|.|....|.|. |     |.:.||   :||::
Zfish   432 HSSQRLEALPGLPSMPALPSSQSYCPSSYSSPGYSVDHVA 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645	80/124 (65%)
		COG5576	<253..368	CDD:227863	47/116 (41%)
		Homeobox	269..322	CDD:395001	33/52 (63%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	80/124 (65%)
		Homeobox	223..276	CDD:278475	32/52 (62%)
		Pax7	350..394	CDD:289156	12/49 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810