Protein Alignment toy and otx2b

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571326.1
• Gene: otx2b / 30501
• ZFINID: ZDB-GENE-980526-406
• Length: 289
• Species: Danio rerio
• Alignment Length: 228
• Identity: 69/228 - (30%)
• Similarity: 114/228 - (50%)
• Gaps: 32/228 - (14%)

  Fly   263 RKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEKMR 327
            ||.:|.||:|:..|:|.||..|.:|.|||:|.||.:|.||.|||:|:||||.|||||.|::::.:
Zfish    36 RKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQQ 100

  Fly   328 ----------TQRRSADTVDGSGRTSTANNPSGTTASSSVATSNNSTPGIVNSAINVAE-----R 377
                      .:::|:...:.|..:..:...:..:::|..|.|..:.|..:.|..:::.     .
Zfish   101 QNGGQNKVRPAKKKSSPAREASSESGASGQFTPPSSTSVPAISTTTAPVSIWSPASISPLSDPLS 165

  Fly   378 TSSALVSNSLP----EASN------GPT-VLGG-EANTTHTSSESPPLQPAAPRLPLNSGFNTMY 430
            |||:.:..|.|    :||.      |.| ..|| :..:..|........|.:...|::|  |.:.
Zfish   166 TSSSCMQRSYPMTYTQASGYSQGYAGSTSYFGGMDCGSYLTPMHHQLTGPGSTLSPMSS--NAVT 228

  Fly   431 SSIPQ-PIATMAENYNSS-LG-SMTPSCLQQRD 460
            |.:.| |.:...:.|.:| || :.|..||..:|
Zfish   229 SHLNQSPASLPTQGYGASGLGFNSTADCLDYKD 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	41/114 (36%)
		Homeodomain	267..322	CDD:459649	32/54 (59%)
otx2b	NP_571326.1	Homeodomain	39..94	CDD:459649	32/54 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..142		4/48 (8%)
		TF_Otx	153..234	CDD:427350	18/82 (22%)