Protein Alignment toy and otx1

DIOPT Version :10

• Sequence 1: NP_001368990.1
• Gene: toy / 43833
• FlyBaseID: FBgn0019650
• Length: 655
• Species: Drosophila melanogaster
• Sequence 2: NP_571325.2
• Gene: otx1 / 30500
• ZFINID: ZDB-GENE-980526-400
• Length: 323
• Species: Danio rerio
• Alignment Length: 261
• Identity: 81/261 - (31%)
• Similarity: 123/261 - (47%)
• Gaps: 49/261 - (18%)

  Fly   263 RKLQRNRTSFSNEQIDSLEKEFERTHYPDVFARERLADKIGLPEARIQVWFSNRRAKWRREEK-- 325
            ||.:|.||:|:..|:|.||..|.:|.|||:|.||.:|.||.|||:|:||||.|||||.|::::
Zfish    36 RKQRRERTTFTRSQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQSG 100

  Fly   326 MRTQRRSADTVDGSGRTSTANNPSG--------TTASSSVATSNNSTPGIVNSAINVAERTSSAL 382
            ..|:.|.|.......|.||.:..||        :..|||.::|:.:..||.:::.:::  |.|::
Zfish   101 SSTKTRPAKKKSSPTRESTGSESSGQFTPPAVSSAGSSSSSSSSTNNTGICSTSTSIS--TVSSI 163

  Fly   383 VSNSLPEASNGPTVLGGEANTTHTSSESPPLQPAAPRLPLNSGFNTMYSSIPQPIATMAENYNS- 446
            .|.::...|..|:|           |...|:.|:.......|...|..|:.|.|       ||.
Zfish   164 WSPAISPGSAPPSV-----------SLPEPVAPSNTSCMQRSVSGTASSTYPMP-------YNQT 210

  Fly   447 ---SLGSMTPSCLQQRDAYPYMFHDPLSLGSPYVS---AHHRNTACNPSAAHQQP--PQHGVYTN 503
               |.|..|||         ..:...:..|| |::   :||.....:|..|...|  |.|.:..:
Zfish   211 TGYSQGYPTPS---------GSYFSGVDCGS-YLAPMHSHHHPHQLSPMTASSMPTHPHHHISQS 265

  Fly   504 S 504
            |
Zfish   266 S 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
toy	NP_001368990.1	PAX	29..153	CDD:128645
		COG5576	<253..368	CDD:227863	48/114 (42%)
		Homeodomain	267..322	CDD:459649	32/54 (59%)
otx1	NP_571325.2	Homeodomain	39..95	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..155		17/63 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..204		9/46 (20%)
		TF_Otx	172..258	CDD:427350	26/113 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	239..277		8/28 (29%)